Publication Name	World Journal of Gastroenterology
Manuscript ID	16541
Country	United States

Received	2015-01-22 08:18
Peer-Review Started	2015-01-22 09:03
To Make the First Decision	2015-02-10 15:30
Return for Revision	2015-02-12 14:10
Revised	2015-02-27 14:43
Second Decision	2015-04-07 08:36
Accepted by Journal Editor-in-Chief	2015-04-09 22:02
Accepted by Company Editor-in-Chief	2015-04-17 15:15
Articles in Press	2015-04-17 16:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-12 17:30
Publish the Manuscript Online	2015-06-29 16:33

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Low yield of routine duodenal biopsies for evaluation of abdominal pain
Manuscript Source	Unsolicited Manuscript
All Author List	Sterling M Dubin, Wilson T Kwong, Denise Kalmaz and Thomas J Savides
Funding Agency and Grant Number
Corresponding Author	Sterling M Dubin, MD, Department of Medicine, Division of Gastroenterology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0956, United States. sterling.dubin@gmail.com
Key Words	Duodenum; Celiac disease; Esophagogastroduodenoscopy; Abdominal pain; Anemia; Iron deficiency anemia; Diarrhea
Core Tip	Duodenal biopsy is commonly performed, yet the diagnostic yield of routine duodenal biopsy of normal appearing duodenal mucosa for the evaluation of abdominal pain is unclear. This retrospective chart review of 300 consecutive patients with duodenal biopsy of normal appearing mucosa performed for evaluation of abdominal pain found a diagnostic yield of 1.3%. There were 3 new diagnoses of celiac disease and one of giardiasis. Routine biopsy of normal appearing duodenal mucosa during esophagogastroduodenoscopy should be reserved for patients with a high pretest probability of duodenal pathology given a low diagnostic yield.
Publish Date	2015-06-29 16:33
Citation	Dubin SM, Kwong WT, Kalmaz D, Savides TJ. Low yield of routine duodenal biopsies for evaluation of abdominal pain. World J Gastroenterol 2015; 21(24): 7495-7499
URL	http://www.wjgnet.com/1007-9327/full/v21/i24/7495.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i24.7495

Full Article (PDF)	WJG-21-7495.pdf
Full Article (Word)	WJG-21-7495.doc
Manuscript File	16541-Review.docx
Answering Reviewers	16541-Answering reviewers.pdf
Audio Core Tip	16541-Audio core tip.mp3
Biostatistics Review Certificate	16541-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	16541-Conflict-of-interest statement.pdf
Copyright License Agreement	16541-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	16541-Institutional review board statement.pdf
Peer-review Report	16541-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16541-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16541-Scientific misconduct check.pdf
Scientific Editor Work List	16541-Scientific editor work list.pdf