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Articles Published Processes
6/29/2015 4:40:00 PM | Browse: 1247 | Download: 2998
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Received |
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2015-01-23 08:46 |
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Peer-Review Started |
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2015-01-24 11:07 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2015-03-17 11:30 |
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Revised |
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2015-03-31 18:27 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2015-05-04 08:30 |
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Second Decision by Editor-in-Chief |
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2015-05-07 23:18 |
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Final Decision by Editorial Office Director |
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2015-05-21 17:40 |
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Articles in Press |
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2015-05-21 17:41 |
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Edit the Manuscript by Language Editor |
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2015-05-22 19:32 |
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Typeset the Manuscript |
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2015-06-12 13:42 |
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Publish the Manuscript Online |
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2015-06-29 16:33 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Evolution of nonspecific duodenal lymphocytosis over 2 years of follow-up
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Giuseppe Losurdo, Domenico Piscitelli, Antonio Giangaspero, Mariabeatrice Principi, Francesca Buffelli, Floriana Giorgio, Lucia Montenegro, Claudia Sorrentino, Annacinzia Amoruso, Enzo Ierardi and Alfredo Di Leo |
| Funding Agency and Grant Number |
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| Corresponding Author |
Enzo Ierardi, Professor, Gastroenterology Section, Department of Emergency and Organ Transplantation, University of Bari, Policlinico, Piazza Giulio Cesare, 70124 Bari, Italy. ierardi.enzo@gmail.com |
| Key Words |
Duodenal lymphocytosis; Celiac disease; Gluten sensitivity; Seronegative celiac disease; Intraepithelial lymphocytes; Immunohistochemistry |
| Core Tip |
Duodenal lymphocytosis may pose a diagnostic challenge since it could be associated with different pathological conditions, which may or may not be related to gluten. In the present study, we demonstrated that during 2 years of follow-up of 85 patients with duodenal lymphocytosis, 27% developed celiac disease and 22% had a clinical diagnosis of gluten sensitivity; the remaining patients were affected by non-gluten-related conditions. At multivariate analysis, the haplotype DQ2/8 and the density of the intraepithelial CD3 lymphocyte infiltrate were the best predictors of the future development of gluten-related disorders. |
| Publish Date |
2015-06-29 16:33 |
| Citation |
Losurdo G, Piscitelli D, Giangaspero A, Principi M, Buffelli F, Giorgio F, Montenegro L, Sorrentino C, Amoruso A, Ierardi E, Di Leo A. Evolution of nonspecific duodenal lymphocytosis over 2 years of follow-up. World J Gastroenterol 2015; 21(24): 7545-7552 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i24/7545.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i24.7545 |
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