BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
7/30/2015 11:19:00 AM | Browse: 1135 | Download: 2510
Publication Name World Journal of Gastroenterology
Manuscript ID 16604
Country South Korea
Received
2015-01-24 20:56
Peer-Review Started
2015-01-25 15:22
To Make the First Decision
2015-02-10 15:30
Return for Revision
2015-02-12 14:36
Revised
2015-03-30 00:00
Second Decision
2015-04-07 08:33
Accepted by Journal Editor-in-Chief
2015-04-07 15:53
Accepted by Company Editor-in-Chief
2015-04-09 17:05
Articles in Press
2015-04-09 17:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-05-04 09:53
Typeset the Manuscript
2015-07-07 17:02
Publish the Manuscript Online
2015-07-30 11:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Restraint stress induces and exacerbates intestinal inflammation in interleukin-10 deficient mice
Manuscript Source Unsolicited Manuscript
All Author List Seong-Joon Koh, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee and Joo Sung Kim
Funding Agency and Grant Number
Funding Agency Grant Number
SNUH Research Fund 06-2011-1770
Basic Science Research Program through the National Research Foundation of Korea NRF-2014R1A1A2057695
Corresponding Author Joo Sung Kim, MD, PhD, Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul 110-744, South Korea. jooskim@snu.ac.kr
Key Words Stress; Colitis; Interleukin-10; Inflammatory bowel disease; Mouse model
Core Tip we investigated the effect of restraint stress on the development and worsening of bowel inflammation in interleukin (IL)-10-/- mice and developed a novel animal model. this is the first study to demonstrate the effect of restrain stress in inducing and exacerbating chronic colitis in IL-10-/- mice. We believe that this novel animal model could be useful in future study of psychological stress in the pathogenesis of inflammatory bowel disease because this model develops chronic colitis due to interaction of genetic, immune dysregulation, microbial environment, and stress factor.
Publish Date 2015-07-30 11:17
Citation Koh SJ, Kim JW, Kim BG, Lee KL, Kim JS. Restraint stress induces and exacerbates intestinal inflammation in interleukin-10 deficient mice. World J Gastroenterol 2015; 21(28): 8580-8587
URL http://www.wjgnet.com/1007-9327/full/v21/i28/8580.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i28.8580
Full Article (PDF) WJG-21-8580.pdf
Full Article (Word) WJG-21-8580.doc
Manuscript File 16604-Review.docx
Answering Reviewers 16604-Answering reviewers.pdf
Biostatistics Review Certificate 16604-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 16604-Conflict-of-interest statement.pdf
Copyright License Agreement 16604-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 16604-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 16604-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate Editing_Certificate_20150124144431.pdf
Peer-review Report 16604-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 16604-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 16604-Scientific misconduct check.pdf
Scientific Editor Work List 16604-Scientific editor work list.pdf