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Articles Published Processes
9/18/2015 10:11:00 AM | Browse: 1293 | Download: 2098
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Received |
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2015-01-26 19:43 |
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Peer-Review Started |
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2015-01-27 09:08 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2015-02-13 11:23 |
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Revised |
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2015-04-01 17:00 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2015-06-01 07:52 |
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Second Decision by Editor-in-Chief |
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2015-06-03 06:26 |
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Final Decision by Editorial Office Director |
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2015-06-10 16:06 |
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Articles in Press |
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2015-06-10 16:06 |
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Edit the Manuscript by Language Editor |
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2015-08-25 17:05 |
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Typeset the Manuscript |
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2015-09-02 11:50 |
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Publish the Manuscript Online |
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2015-09-18 10:11 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Natural evolution of hepatitis C virus infection in hemodialysis Tunisian patients and CTLA-4 SNP's
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Leila Ksiaa Cheikhrouhou, Yousr Lakhoua-Gorgi, Imen Sfar, Salwa Jendoubi-Ayed, Houda Aouadi, Mouna Makhlouf, Khaled Ayed and Taieb Ben Abdallah |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Tunisian Kidney Transplantation Research Laboratory |
LR03SP01 |
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| Corresponding Author |
Leila Ksiaa Cheikhrouhou, PhD, Laboratory of Immunology, Charles Nicolle Hospital, Boulevard 9 Avril, 1006 Tunis, Tunisia. ksiaaleila@yahoo.fr |
| Key Words |
Hepatitis C virus; Hemodialysis; Natural evolution; CTLA-4 polymorphisms |
| Core Tip |
Clinical and virological characteristics of our cohort suggest a nosocomial hepatitis C virus (HVC) infection in Tunisian hemodialysis patients with transfusion history as primary risk factor and a predominance of genotype 1b. No significant association was found for the two CTLA-4 SNP’s studied either to spontaneous clearance, persistence or protection against HCV infection. The GG (+49) / (CT60) CTLA-4 haplotype is therefore associated with susceptibility to HCV infection. The study of other susceptibility genes for HCV infection will certainly allow a better understanding of the molecular mechanisms of spontaneous viral clearance or persistence of HCV infection. |
| Publish Date |
2015-09-18 10:11 |
| Citation |
Ksiaa Cheikhrouhou L, Lakhoua-Gorgi Y, Sfar I, Jendoubi-Ayed S, Aouadi H, Makhlouf M, Ayed K, Ben Abdallah T. Natural evolution of hepatitis C virus infection in hemodialysis Tunisian patients and CTLA-4 SNP’s. World J Gastroenterol 2015; 21(35): 10150-10158
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| URL |
http://www.wjgnet.com/1007-9327/full/v21/i35/10150.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i35.10150 |
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