Publication Name	World Journal of Gastroenterology
Manuscript ID	16676
Country	China

Received	2015-01-27 08:50
Peer-Review Started	2015-01-27 09:32
To Make the First Decision	2015-02-10 15:52
Return for Revision	2015-02-13 11:23
Revised	2015-02-24 00:00
Second Decision	2015-03-25 17:08
Accepted by Journal Editor-in-Chief	2015-03-26 00:17
Accepted by Executive Editor-in-Chief	2015-03-31 10:12
Articles in Press	2015-03-31 11:07
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-04-30 04:47
Typeset the Manuscript	2015-05-22 16:35
Publish the Manuscript Online	2015-06-11 10:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Different treatment strategies and molecular features between right-sided and left-sided colon cancers
Manuscript Source	Invited Manuscript
All Author List	Hong Shen, Jiao Yang, Qing Huang, Meng-Jie Jiang, Yi-Nuo Tan, Jian-Fei Fu, Li-Zhen Zhu, Xue-Feng Fang and Ying Yuan
Funding Agency and Grant Number	Funding Agency Grant Number Key Projects in the National Science and Technology Pillar Program during the Twelfth Five-year Plan Period 2014BAI09B07 National Natural Science Foundation of China 81101580 National Natural Science Foundation of China 81201640
Corresponding Author	Ying Yuan, Professor, Department of Medical Oncology, 2nd Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. yuanying1999@zju.edu.cn
Key Words	Colon cancer; Right; Left; Survival; Molecular
Core Tip	The colon is derived from the embryological midgut and hindgut separately, with the right colon and left colon having different features with regards to anatomical and physiological characteristics. Based on the location, colon cancers are referred to as either right colon cancer (RCC) or left colon cancer (LCC), respectively, with both having distinct clinical manifestations. Increasing evidence supports the notion that differences exist in terms of sensitivity to adjuvant, palliative, and targeted treatments between RCC and LCC. In further analysis, significant varieties exist at the molecular level between RCC and LCC. Therefore, RCC and LCC should be regarded as two heterogeneous entities. Clinically, this heterogeneity is highly beneficial in therapeutic decision-making.
Publish Date	2015-06-11 10:11
Citation	Shen H, Yang J, Huang Q, Jiang MJ, Tan YN, Fu JF, Zhu LZ, Fang XF, Yuan Y. Different treatment strategies and molecular features between right-sided and left-sided colon cancers. World J Gastroenterol 2015; 21(21): 6470-6478
URL	http://www.wjgnet.com/1007-9327/full/v21/i21/6470.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i21.6470

Full Article (PDF)	WJG-21-6470.pdf
Full Article (Word)	WJG-21-6470.doc
Manuscript File	16676-Review.docx
Answering Reviewers	16676-Answering reivewers.pdf
Audio Core Tip	16676-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	16676-Conflict-of-interest statement.pdf
Copyright License Agreement	16676-Copyright assignment.pdf
Peer-review Report	16676-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16676-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16676-Scientific misconduct check.pdf
Scientific Editor Work List	16676-Scientific editor work list.pdf