Publication Name	World Journal of Dermatology
Manuscript ID	16679
Country	Taiwan

Received	2015-01-27 08:45
Peer-Review Started	2015-01-28 11:42
To Make the First Decision	2015-03-06 10:30
Return for Revision	2015-03-11 12:22
Revised	2015-03-16 00:19
Second Decision	2015-04-01 15:03
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-04-09 16:52
Articles in Press	2015-04-09 16:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-15 08:41
Publish the Manuscript Online	2015-04-28 10:28

ISSN	2218-6190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Dermatology
Manuscript Type	Editorial
Article Title	Mycosis fungoides and Sézary syndrome: Role of chemokines and chemokine receptors
Manuscript Source	Invited Manuscript
All Author List	Stephen Chu-Sung Hu
Funding Agency and Grant Number
Corresponding Author	Stephen Chu-Sung Hu, MBBS, M.Phil, Department of Dermatology, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Road, Kaohsiung 807, Taiwan. stephenhu30@hotmail.com
Key Words	Mycosis fungoides; Sézary syndrome; Skin-homing; Chemokines; Chemokine receptors
Core Tip	Mycosis fungoides and Sézary syndrome are characterized by a clonal expansion of malignant CD4+ T lymphocytes with skin-homing properties. Currently, treatment options for mycosis fungoides and Sézary syndrome are limited. The lack of effective targeted therapy results in part from the poor understanding regarding the pathophysiology of these diseases. Recently, a number of chemokines and chemokine receptors have been found to contribute to the pathogenesis of mycosis fungoides and Sézary syndrome, including the CC chemokine receptor 4 (CCR4)/chemokine (C-C motif) ligand 17 (CCL17), CCR10/CCL27, C-X-C chemokine receptor type 4/chemokine (C-X-C Motif) ligand 12 and CCR7/CCL21 axes. Therefore, these chemokines and chemokine receptors may be potentially useful targets for the treatment of these lymphomas in the future.
Publish Date	2015-04-28 10:28
Citation	Hu SC. Mycosis fungoides and Sézary syndrome: Role of chemokines and chemokine receptors. World J Dermatol 2015; 4(2): 69-79
URL	http://www.wjgnet.com/2218-6190/full/v4/i2/69.htm
DOI	http://dx.doi.org/10.5314/wjd.v4.i2.69

Full Article (PDF)	WJD-4-69.pdf
Full Article (Word)	WJD-4-69.doc
Manuscript File	16679-Review.doc
Answering Reviewers	16679-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	16679-Conflict-of-interest statement.pdf
Copyright License Agreement	16679-Copyright assignment.pdf
Peer-review Report	16679-Peer-review(s).pdf
Scientific Misconduct Check	16679-Scientific misconduct check.pdf
Scientific Editor Work List	16679-Scientific editor work list.pdf