Publication Name	World Journal of Biological Chemistry
Manuscript ID	16688
Country	United States

Received	2015-01-27 09:55
Peer-Review Started	2015-01-28 18:12
To Make the First Decision	2015-03-06 10:30
Return for Revision	2015-03-11 17:05
Revised	2015-03-18 03:32
Second Decision	2015-04-09 16:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-04-20 14:24
Articles in Press	2015-04-20 14:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-05-04 08:39
Publish the Manuscript Online	2015-05-21 13:33

ISSN	1949-8454 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Biochemistry & Molecular Biology
Manuscript Type	Minireviews
Article Title	Adipocyte activation of cancer stem cell signaling in breast cancer
Manuscript Source	Invited Manuscript
All Author List	Benjamin Wolfson, Gabriel Eades and Qun Zhou
Funding Agency and Grant Number
Corresponding Author	Qun Zhou, MD, PhD, Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201, United States. qzhou@som.umaryland.edu
Key Words	Breast cancer; Interleukin-6; Cancer stem cells; Adipocyte; Microenvironment; Epithelial-mesenchymal transition; Leptin
Core Tip	We discuss the relationship between adipocytes in the microenvironment and breast cancer cells. We emphasize the role of adipocyte-secreted leptin and interleukin-6 in inducing breast cancer cell epithelial-mesenchymal transition and activating stemness pathways. Finally we summarize possible microenvironmental therapeutic targets and the potential role of non-coding RNAs in adipocyte-breast cancer interactions.
Publish Date	2015-05-21 13:33
Citation	Wolfson B, Eades G, Zhou Q. Adipocyte activation of cancer stem cell signaling in breast cancer. World J Biol Chem 2015; 6(2): 39-47
URL	http://www.wjgnet.com/1949-8454/full/v6/i2/39.htm
DOI	http://dx.doi.org/10.4331/wjbc.v6.i2.39

Full Article (PDF)	WJBC-6-39.pdf
Full Article (Word)	WJBC-6-39.doc
Manuscript File	16688-Review.docx
Answering Reviewers	16688-Answering reviewers.pdf
Audio Core Tip	16688-Audio core tip.wav
Conflict-of-Interest Disclosure Form	16688-Conflict-of-interest statement.pdf
Copyright License Agreement	16688-Copyright assignment.pdf
Peer-review Report	16688-Peer-review(s).pdf
Scientific Misconduct Check	16688-Scientific misconduct check.pdf
Scientific Editor Work List	16688-Scientific editor work list.pdf