Publication Name	World Journal of Methodology
Manuscript ID	16715
Country	Australia

Received	2015-01-28 10:44
Peer-Review Started	2015-01-28 19:56
To Make the First Decision	2015-03-06 10:29
Return for Revision	2015-03-11 17:53
Revised	2015-04-05 00:31
Second Decision	2015-06-12 16:29
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-06-19 17:50
Articles in Press	2015-06-19 17:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-31 15:17
Publish the Manuscript Online	2015-09-16 14:40

ISSN	2222-0682 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Pediatrics
Manuscript Type	Systematic Reviews
Article Title	Early probiotics to prevent childhood metabolic syndrome: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Haribalakrishna Balasubramanian and Sanjay Patole
Funding Agency and Grant Number
Corresponding Author	Sanjay Patole, Professor, Department of Neonatal Paediatrics, KEM Hospital for Women, 374 Bagot Road, Subiaco, Perth WA 6008, Australia. sanjay.patole@health.wa.gov.au
Key Words	Metabolic syndrome; Obesity; Probiotic; Infant; Perinatal; Children
Core Tip	Metabolic syndrome (MS) is a state of dysregulated glucose and lipid metabolism. The global health burden due to increasing prevalence of MS in children and adolescents, warrants urgent preventive interventions. Altered gut microbiota has been implicated in the pathogenesis of MS. The role of maternal and/or infant probiotic supplementation in improving metabolic health of the offspring is being researched. We provide a systematic review of this evidence. Gaps in the knowledge and issues regarding selection of patient population, probiotic intervention and outcomes for future trials have been discussed.
Publish Date	2015-09-16 14:40
Citation	Balasubramanian H, Patole S. Early probiotics to prevent childhood metabolic syndrome: A systematic review. World J Methodol 2015; 5(3): 157-163
URL	http://www.wjgnet.com/2222-0682/full/v5/i3/157.htm
DOI	http://dx.doi.org/10.5662/wjm.v5.i3.157

Full Article (PDF)	WJM-5-157.pdf
Full Article (Word)	WJM-5-157.doc
Manuscript File	16715-Review.docx
Answering Reviewers	16715-Answering reviewers.pdf
Audio Core Tip	16715-Audio core tip.wma
Biostatistics Review Certificate	16715-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	16715-Conflict-of-interest statement.pdf
Copyright License Agreement	16715-Copyright assignment.pdf
Peer-review Report	16715-Peer-review(s).pdf
Scientific Misconduct Check	16715-Scientific misconduct check.pdf
Scientific Editor Work List	16715-Scientific editor work list.pdf