Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	16757
Country	Hungary

Received	2015-01-29 09:47
Peer-Review Started	2015-02-01 19:12
First Decision by Editorial Office Director
Return for Revision	2015-03-15 18:39
Revised	2015-03-27 20:34
Publication Fee Transferred
Second Decision by Editor	2015-05-25 11:55
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2015-06-02 17:43
Articles in Press	2015-06-02 17:43
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-23 12:28
Publish the Manuscript Online	2015-08-17 16:11

ISSN	2150-5330 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Neurosciences
Manuscript Type	Editorial
Article Title	Gut region-dependent alterations of nitrergic myenteric neurons after chronic alcohol consumption
Manuscript Source	Invited Manuscript
All Author List	Mária Bagyánszki and Nikolett Bódi
Funding Agency and Grant Number	Funding Agency Grant Number János Bolyai Research Scholarship of the Hungarian Academy of Sciences Mária Bagyánszki Hungarian Scientific Research Fund PD 108309 (to Nikolett Bódi)
Corresponding Author	Mária Bagyánszki, PhD, Department of Physiology, Anatomy and Neuroscience, University of Szeged, Közép fasor 52, 6726 Szeged, Hungary. bmarcsi@bio.u-szeged.hu
Key Words	Chronic ethanol consumption; Nitrergic myenteric neurons; Enteric nervous system; Nitric oxide synthase; Gut motility disorders; Intestinal microbiota
Core Tip	Chronic ethanol administration causes neuro-degeneration in the central nervous system. In the enteric nervous system neurodegeneration was not demonstrated, however alcohol-induced quantitative, functional and neurochemical changes of nitrergic myenteric neurons were observed in gut region-dependent way. These suggest that disturbed gastrointestinal transit characteristic to alcoholic patients due to an impairment of a nitric oxide-medi-a-ted descending inhibition during peristalsis. The better understanding of the effects of chronic ethanol administration on enteric neurons may reveal new targets for therapy.
Publish Date	2015-08-17 16:11
Citation	Bagyánszki M, Bódi N. Gut region-dependent alterations of nitrergic myenteric neurons after chronic alcohol consumption. World J Gastrointest Pathophysiol 2015; 6(3): 51-57
URL	http://www.wjgnet.com/2150-5330/full/v6/i3/51.htm
DOI	http://dx.doi.org/10.4291/wjgp.v6.i3.51

Full Article (PDF)	WJGP-6-51.pdf
Full Article (Word)	WJGP-6-51.doc
Manuscript File	16757-Review.docx
Answering Reviewers	16757-Answering reviewers.PDF
Audio Core Tip	16757-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	16757-Conflict-of-interest statement.PDF
Copyright License Agreement	16757-Copyright assignment.pdf
Peer-review Report	16757-Peer-review(s).pdf
Scientific Misconduct Check	16757-Scientific misconduct check.pdf
Scientific Editor Work List	16757-Scientific editor work list.pdf