Publication Name	World Journal of Cardiology
Manuscript ID	16821
Country	Italy

Received	2015-01-29 15:59
Peer-Review Started	2015-01-29 17:29
To Make the First Decision	2015-03-06 10:27
Return for Revision	2015-03-11 19:56
Revised	2015-03-13 16:07
Second Decision	2015-04-09 16:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-04-20 14:26
Articles in Press	2015-04-20 14:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-10 14:44
Publish the Manuscript Online	2015-06-25 15:27

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Allergy
Manuscript Type	Minireviews
Article Title	Closing patent foramen ovale in cryptogenic stroke: The underscored importance of other interatrial shunt variants
Manuscript Source	Invited Manuscript
All Author List	Gianluca Rigatelli and Alberto Rigatelli
Funding Agency and Grant Number
Corresponding Author	Gianluca Rigatelli, MD, PhD, Section of Adult Congenital and Adult Heart Disease, Cardiovascular Diagnosis and Endoluminal Interventions, Rovigo General Hospital, Viale Tre martiri, 45100 Rovigo, Italy. jackyheart71@yahoo.it
Key Words	Atrial septal defect; Patent foramen ovale; Echocardiography; Anatomy
Core Tip	Recent trials and met analysis suggested that mechanical device-based closure of patent foramen ovale (PFO) is more effective than medical therapy in prevent recurrence of stroke. Fenestrated atrial septal aneurysms and small atrial septal defects (hybrid defects) can present with signs of paradoxical embolism and because they are often not clearly differentiable by standard diagnostic tools, it is likely that a proportion of patients evaluated for transcatheter closure of PFO, had actually a different anatomical substrate. These different anatomical entities have not been address in any of the previous trials, potentially having an impact on overall results.
Publish Date	2015-06-25 15:27
Citation	Rigatelli G, Rigatelli A. Closing patent foramen ovale in cryptogenic stroke: The underscored importance of other interatrial shunt variants. World J Cardiol 2015; 7(6): 326-330
URL	http://www.wjgnet.com/1949-8462/full/v7/i6/326.htm
DOI	http://dx.doi.org/10.4330/wjc.v7.i6.326

Full Article (PDF)	WJC-7-326.pdf
Manuscript File	16821-Review.doc
Answering Reviewers	16821-Answering reviewers.pdf
Audio Core Tip	16821-Audio core tip.wav
Conflict-of-Interest Disclosure Form	16821-Conflict-of-interest statement.pdf
Copyright License Agreement	16821-Copyright assignment.pdf
Peer-review Report	16821-Peer-review(s).pdf
Scientific Misconduct Check	16821-Scientific misconduct check.pdf
Scientific Editor Work List	16821-Scientific editor work list.pdf