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Articles Published Processes
12/15/2015 10:11:00 AM | Browse: 980 | Download: 1511
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Received |
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2015-01-29 21:23 |
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Peer-Review Started |
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2015-01-30 19:18 |
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To Make the First Decision |
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2015-03-06 10:27 |
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Return for Revision |
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2015-03-11 20:01 |
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Revised |
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2015-03-24 13:45 |
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Second Decision |
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2015-04-22 17:15 |
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Accepted by Journal Editor-in-Chief |
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2015-04-22 18:07 |
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Accepted by Executive Editor-in-Chief |
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2015-09-30 18:31 |
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Articles in Press |
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2015-09-30 18:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-12-03 13:14 |
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Publish the Manuscript Online |
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2015-12-15 10:10 |
ISSN |
2222-0682 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Respiratory System |
Manuscript Type |
Minireviews |
Article Title |
Forkhead box protein A2 and T helper type 2-mediated pulmonary inflammation
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Manuscript Source |
Invited Manuscript |
All Author List |
Ling Sun, Xiao-Ju Tang and Feng-Ming Luo |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
30871118 |
National Natural Science Foundation of China |
30971325 |
National Natural Science Foundation of China |
81270129 |
National Natural Science Foundation of China |
81470268 (FL) |
Department of Science and Technology of Sichuan Province |
09ZQ026-020 |
Department of Science and Technology of Sichuan Province |
2009SZ0190 (FL) |
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Corresponding Author |
Feng-Ming Luo, MD, PhD, Department of Family Medicine, West China Hospital, Sichuan University, 37 GuoXue Xiang, Chengdu 610041, Sichuan Province,
China. luofengming@hotmail.com
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Key Words |
Forkhead box protein A2; T helper type 2 inflammation; Pulmonary; Development; Goblet cell hyperplasia |
Core Tip |
The transcription factor forkhead box protein A2 (FOXA2) plays pivotal roles in embryonic development and organogenesis. Conditional deletion of FOXA2 in airway epithelial cells during the early stage of lung development will result in abnormal morphology of the lung and T helper type 2-mediated pulmonary inflammation. In addition, FOXA2 regulates the goblet cell differentiation during lung development and in pulmonary diseases such as asthma and chronic obstructive pulmonary disease. FOXA2 may be a new target for the treatment of lung disease. |
Publish Date |
2015-12-15 10:10 |
Citation |
Sun L, Tang XJ, Luo FM. Forkhead box protein A2 and T helper type 2-mediated pulmonary inflammation. World J Methodol 2015; 5(4): 223-229 |
URL |
http://www.wjgnet.com/2222-0682/full/v5/i4/223.htm |
DOI |
http://dx.doi.org/10.5662/wjm.v5.i4.223 |
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