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Articles Published Processes
7/30/2015 11:19:00 AM | Browse: 1055 | Download: 2399
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Received |
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2015-01-30 08:27 |
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Peer-Review Started |
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2015-01-30 15:34 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2015-03-16 09:04 |
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Revised |
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2015-03-26 19:20 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2015-04-23 08:25 |
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Second Decision by Editor-in-Chief |
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2015-04-23 16:03 |
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Final Decision by Editorial Office Director |
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2015-05-04 18:10 |
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Articles in Press |
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2015-05-04 18:10 |
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Edit the Manuscript by Language Editor |
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2015-05-17 23:19 |
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Typeset the Manuscript |
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2015-07-06 18:25 |
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Publish the Manuscript Online |
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2015-07-30 11:17 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Hepatitis B surface antigen levels of cessation of nucleos(t)ide analogs associated with virological relapse in hepatitis B surface antigen-negative chronic hepatitis B patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Guo-Hong Ge, Yun Ye, Xin-Bei Zhou, Li Chen, Cong He, Dan-Feng Wen and You-Wen Tan |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Jiangsu Province, China |
BK2011515 |
| Medical Project of Health Department Jiangsu Province |
H201248 |
| Preventive Medicine research projects of Jiangsu Province |
Y2012016 |
| Social Development Project of Zhenjiang City |
SH2013056 |
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| Corresponding Author |
Yun Ye, Associate Professor, Department of Hepatosis, The Third Hospital of Zhenjiang Affiliated Jiangsu University, No. 300 Daijiamen, Runzhou Distinct, Zhenjiang 212000, Jiangsu Province, China. tyw915@sina.com |
| Key Words |
Chronic hepatitis B; Virological relapse; Hepatitis B surface antigen |
| Core Tip |
To study the rate of virological relapse in hepatitis B e antigen (HBeAg)-negative patients after stopping antiviral therapy. Two hundred and four patients were eligible for this analysis. The cumulative probability of virological relapse after stopping antiviral therapy was 79.41% (162/204) in 2 years and 43.82% (71/162) in 1 year. Cumulative probability of virological relapse in levels of the hepatitis B surface antigen (HBsAg) ≥ 1500IU/L group was higher than that of levels of the HBsAg < 1500 IU/L group. The cutoff value for predicting virological relapse was 1443 IU/L. We found that the virological relapse rate maintained a high level after stopping NUCs in HBeAg-negative patients and HBsAg levels of cessation of nucleos(t)ide analogs predicted virological relapse. |
| Publish Date |
2015-07-30 11:17 |
| Citation |
Ge GH, Ye Y, Zhou XB, Chen L, He C, Wen DF, Tan YW. Hepatitis B surface antigen levels of cessation of nucleos(t)ide analogs associated with virological relapse in hepatitis B surface antigen-negative chronic hepatitis B patients. World J Gastroenterol 2015; 21(28): 8653-8659 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i28/8653.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i28.8653 |
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