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9/18/2015 10:11:00 AM | Browse: 685 | Download: 1022
Publication Name World Journal of Gastroenterology
Manuscript ID 16885
Country of Manuscript Source Canada
2015-02-03 09:50
Peer-Review Started
2015-02-08 15:13
To Make the First Decision
2015-03-10 17:33
Return for Revision
2015-03-16 09:07
2015-03-27 11:58
Second Decision
2015-04-23 08:26
Accepted by Journal Editor-in-Chief
2015-04-23 12:07
Accepted by Company Editor-in-Chief
2015-05-04 18:12
Articles in Press
2015-05-04 18:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-09-01 11:00
Publish the Manuscript Online
2015-09-18 10:11
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Nutrition and Dietetics
Manuscript Type Basic Study
Article Title Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease
Manuscript Source Unsolicited Manuscript
All Author List John J Miklavcic, Tasha DL Hart, Gordon M Lees, Glen K Shoemaker, Kareena L Schnabl, Bodil MK Larsen, Oliver F Bathe, Alan BR Thomson, Vera C Mazurak and M Tom Clandinin
Funding Agency and Grant Number
Funding Agency Grant Number
Natural Sciences and Engineering Research Council of Canada
Broad Foundation
Canadian Institutes of Health Research
Alberta Livestock and Meat Agency
Corresponding author Dr. M Tom Clandinin, Department of AFNS, Distinguished University Professor Emeritus, Alberta Institute for Human Nutrition, Faculty of ALES, University of Alberta, 116 St. 85 Ave, Edmonton AB T6G 2R1, Canada. tclandin@ualberta.ca
Keywords Ganglioside; Phospholipid; Fatty acid; Lipid; Inflammatory bowel disease; Inflammation; Nutrition; Crohn’s disease; Ulcerative colitis
Core Tip This research suggests a new paradigm by proposing that increased metabolism of specific gangliosides is fundamental to the etiology of inflammatory bowel disease. The study demonstrates that the catabolism of gangliosides is elevated in the intestinal mucosa of patients with inflammatory bowel disease and suggests that intervention with appropriate dietary gangliosides potentially reduces intestinal permeability, improving intestinal integrity.
Publish Date 2015-09-18 10:11
Citation Miklavcic JJ, Hart TDL, Lees GM, Shoemaker GK, Schnabl KL, Larsen BMK, Bathe OF, Thomson ABR, Mazurak VC, Clandinin MT. Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease. World J Gastroenterol 2015; 21(35): 10080-10090
Url http://www.wjgnet.com/1007-9327/full/v21/i35/10080.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i35.10080
Full Article (PDF) WJG-21-10080.pdf
Full Article (Word) WJG-21-10080.doc
Manuscript File 16885-Review.doc
Answering Reviewers 16885-Answering reviewers.pdf
Audio Core Tip 16885-Audio core tip.wav
Biostatistics Review Certificate 16885-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 16885-Conflict-of-interest statement.pdf
Copyright License Agreement 16885-Copyright assignment.pdf
Data Sharing Statement 16885-Data sharing statement.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20150201121653.pdf
Institutional Animal Care and Use Committee Approval Form or Document 16885-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 16885-Institutional review board statement.pdf
Peer-review Report 16885-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 16885-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 16885-Scientific misconduct check.pdf
Scientific Editor Work List 16885-Scientific editor work list.pdf