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Articles Published Processes
9/18/2015 10:11:00 AM | Browse: 1318 | Download: 2147
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Received |
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2015-02-03 09:50 |
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Peer-Review Started |
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2015-02-08 15:13 |
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To Make the First Decision |
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2015-03-10 17:33 |
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Return for Revision |
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2015-03-16 09:07 |
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Revised |
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2015-03-27 11:58 |
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Second Decision |
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2015-04-23 08:26 |
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Accepted by Journal Editor-in-Chief |
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2015-04-23 12:07 |
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Accepted by Company Editor-in-Chief |
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2015-05-04 18:12 |
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Articles in Press |
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2015-05-04 18:12 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-09-01 11:00 |
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Publish the Manuscript Online |
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2015-09-18 10:11 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Nutrition & Dietetics |
| Manuscript Type |
Basic Study |
| Article Title |
Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
John J Miklavcic, Tasha DL Hart, Gordon M Lees, Glen K Shoemaker, Kareena L Schnabl, Bodil MK Larsen, Oliver F Bathe, Alan BR Thomson, Vera C Mazurak and M Tom Clandinin |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Sciences and Engineering Research Council of Canada |
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| Broad Foundation |
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| Canadian Institutes of Health Research |
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| Alberta Livestock and Meat Agency |
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| Corresponding Author |
Dr. M Tom Clandinin, Department of AFNS, Distinguished University Professor Emeritus, Alberta Institute for Human Nutrition, Faculty of ALES, University of Alberta, 116 St. 85 Ave, Edmonton AB T6G 2R1,
Canada. tclandin@ualberta.ca |
| Key Words |
Ganglioside; Phospholipid; Fatty acid; Lipid; Inflammatory bowel disease; Inflammation; Nutrition; Crohn’s disease; Ulcerative colitis |
| Core Tip |
This research suggests a new paradigm by proposing that increased metabolism of specific gangliosides is fundamental to the etiology of inflammatory bowel disease. The study demonstrates that the catabolism of gangliosides is elevated in the intestinal mucosa of patients with inflammatory bowel disease and suggests that intervention with appropriate dietary gangliosides potentially reduces intestinal permeability, improving intestinal integrity.
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| Publish Date |
2015-09-18 10:11 |
| Citation |
Miklavcic JJ, Hart TDL, Lees GM, Shoemaker GK, Schnabl KL, Larsen BMK, Bathe OF, Thomson ABR, Mazurak VC, Clandinin MT. Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease. World J Gastroenterol 2015; 21(35): 10080-10090 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i35/10080.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i35.10080 |
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