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10/14/2015 12:06:00 PM | Browse: 503 | Download: 1118
Publication Name World Journal of Gastroenterology
Manuscript ID 16907
Country/Territory South Korea
2015-02-03 09:34
Peer-Review Started
2015-02-05 17:09
To Make the First Decision
2015-03-26 18:26
Return for Revision
2015-03-27 15:57
2015-05-13 15:53
Second Decision
2015-07-17 16:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-07-18 11:08
Articles in Press
2015-07-18 11:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-09-17 15:28
Publish the Manuscript Online
2015-10-14 12:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Management of entecavir-resistant chronic hepatitis B with adefovir-based combination therapies
Manuscript Source Unsolicited Manuscript
All Author List Hyoung Su Kim, Hyung Joon Yim, Myoung Kuk Jang, Ji Won Park, Sang Jun Suh, Yeon Seok Seo, Ji Hoon Kim, Bo Hyun Kim, Sang Jong Park, Sae Hwan Lee, Sang Gyune Kim, Young Seok Kim, Jung Il Lee, Jin-Woo Lee, In Hee Kim, Tae Yeob Kim, Jin-Wook Kim, Sook-Hyang Jeong, Young Kul Jung, Hana Park and Seong Gyu Hwang; on behalf of Antiviral Resistance Study Group
Funding Agency and Grant Number
Funding Agency Grant Number
Korean Association for the Study of the Liver (in part)
Corresponding author Hyung Joon Yim, MD, PhD, Department of Internal Medicine, Korea University Ansan Hospital, 123 Jeokgeum-ro, Danwon-Gu, Ansan-Si, Gyeonggi-Do 425-707, South Korea. gudwns21@medimail.co.kr
Keywords Adefovir; Chronic hepatitis B; Entecavir; Lamivudine; Resistance
Core Tip Studies regarding optimal treatment strategies for entecavir-resistant chronic hepatitis B are sparse. Tenofovir may be the best option, but it is still not available in many countries. Where tenofovir is not available, adefovir plus entecavir can be considered an alternative treatment option in patients with favorable predictive factors. These factors included lower baseline hepatitis B virus (HBV) DNA levels (< 5.2 log10 IU/mL) and reduction of HBV DNA < 3.3 log10 IU/mL after 3 mo of treatment in our study. The present study will guide the treatment of entecavir-resistant chronic hepatitis B.
Publish Date 2015-10-14 12:06
Citation Kim HS, Yim HJ, Jang MK, Park JW, Suh SJ, Seo YS, Kim JH, Kim BH, Park SJ, Lee SH, Kim SG, Kim YS, Lee JI, Lee JW, Kim IH, Kim TY, Kim JW, Jeong SH, Jung YK, Park H, Hwang SG; on behalf of Antiviral Resistance Study Group. Management of entecavir-resistant chronic hepatitis B with adefovir-based combination therapies. World J Gastroenterol 2015; 21(38): 10874-10882
Url http://www.wjgnet.com/1007-9327/full/v21/i38/10874.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i38.10874
Full Article (PDF) WJG-21-10874.pdf
Full Article (Word) WJG-21-10874.doc
Manuscript File 16907-Review.doc
Answering Reviewers 16907-Answering reviewers.pdf
Audio Core Tip 16907-Audio core tip.WAV
Biostatistics Review Certificate 16907-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 16907-Conflict-of-interest statement.pdf
Copyright License Agreement 16907-Copyright assignment.pdf
Data Sharing Statement 16907-Data sharing statement.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20150202133422.pdf
Institutional Review Board Approval Form or Document 16907-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 16907-Language certificate.pdf
Peer-review Report 16907-Peer-review(s).pdf
Scientific Misconduct Check 16907-Scientific misconduct check.pdf
Scientific Editor Work List 16907-Scientific editor work list.pdf