Publication Name	World Journal of Cardiology
Manuscript ID	17039
Country	India

Received	2015-02-09 08:29
Peer-Review Started	2015-02-09 16:46
To Make the First Decision	2015-06-03 14:39
Return for Revision	2015-06-04 16:16
Revised	2015-06-26 13:19
Second Decision	2015-09-28 14:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-10-13 17:41
Articles in Press	2015-10-13 17:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-11 17:36
Publish the Manuscript Online	2015-11-30 08:10

ISSN	1949-8462 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Prospective Study
Article Title	Comparison of echocardiography and device based algorithm for atrio-ventricular delay optimization in heart block patients
Manuscript Source	Unsolicited Manuscript
All Author List	Rajesh Vijayvergiya and Ankur Gupta
Funding Agency and Grant Number
Corresponding Author	Dr. Rajesh Vijayvergiya, MD, DM, FSCAI, FISES, FACC, Profesor, Department of Cardiology, Advanced Cardiac Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India. rajeshvijay999@hotmail.com
Key Words	Atrio-ventricular delay optimization; Complete heart block; Doppler echocardiography; Dual chamber pacemaker; Hemodynamics; QuickOpt algorithm
Core Tip	Optimization of sensed and paced atrio-ventricular (AV/PV) delay is required for better hemodynamics in patients with complete heart block (CHB). Aim of the present study was to compare the AV/PV delay optimization by echocardiography and intra-cardiac electrocardiogram (IEGM) based QuickOpt algorithm in patients with CHB. We prospectively enrolled 20 patients of CHB who were implanted with a dual chamber pacemaker. A velocity time-integral of left ventricular outflow tract was measured following AV/PV delay optimization by both echocardiography and QuickOpt algorithm method. An agreement between the two techniques was assessed by Bland-Altman analysis. Optimal AV and PV delay as assessed by echocardiography was 155.5 ± 14.68 ms and 122.5 ± 17.73 ms (P < 0.0001), respectively and by QuickOpt method was 167.5 ± 16.73 ms and 117.5 ± 9.10 ms (P < 0.0001), respectively. The time required for AV/PV optimization was 45.26 ± 1.73 min by echocardiography and 0.44 ± 0.08 min by QuickOpt method (P < 0.0001). In conclusion, automated programmer based IEGM method is a quick, easy and reliable alternative to echocardiography for optimization of AV/PV delay in CHB patients.
Publish Date	2015-11-30 08:10
Citation	Vijayvergiya R, Gupta A. Comparison of echocardiography and device based algorithm for atrio-ventricular delay optimization in heart block patients. World J Cardiol 2015; 7(11): 801-807
URL	http://www.wjgnet.com/1949-8462/full/v7/i11/801.htm
DOI	http://dx.doi.org/10.4330/wjc.v7.i11.801

Full Article (PDF)	WJC-7-801.pdf
Full Article (Word)	WJC-7-801.doc
Manuscript File	17039-Review.doc
Answering Reviewers	17039-Answering reviewers.pdf
Audio Core Tip	17039-Audio core tip.mp3
Biostatistics Review Certificate	17039-Biostatistics statement.pdf
Clinical Trial Registration Statement	17039-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form	17039-Conflict-of-interest statement.pdf
Copyright License Agreement	17039-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	17039-Clinical trial registration statement.pdf
Institutional Review Board Approval Form or Document	17039-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	17039-Language certificate.pdf
Peer-review Report	17039-Peer-review(s).pdf
Scientific Misconduct Check	17039-Scientific misconduct check.pdf
Scientific Editor Work List	17039-Scientific editor work list.pdf