Publication Name	World Journal of Nephrology
Manuscript ID	17073
Country	France

Received	2015-02-11 09:01
Peer-Review Started	2015-02-11 16:13
To Make the First Decision	2015-03-20 14:32
Return for Revision	2015-03-28 16:48
Revised	2015-04-21 00:00
Second Decision	2015-05-07 09:54
Accepted by Journal Editor-in-Chief	2015-05-07 17:59
Accepted by Executive Editor-in-Chief	2015-05-18 17:02
Articles in Press	2015-05-18 17:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-01 09:57
Publish the Manuscript Online	2015-07-06 18:45

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Urology & Nephrology
Manuscript Type	Minireviews
Article Title	How tubular epithelial cells dictate the rate of renal fibrogenesis?
Manuscript Source	Invited Manuscript
All Author List	Kevin Louis and Alexandre Hertig
Funding Agency and Grant Number
Corresponding Author	Alexandre Hertig, Professor, UPMC Sorbonne Université Paris 06, UMR S 1155, 4 rue de la Chine, F-75020 Paris, France. alexandre.hertig@upmc.fr
Key Words	Epithelium; Fibroblasts; Acute kidney injury; Chronic kidney diseases; Fibrosis
Core Tip	In this review, we explain why and how tubular epithelial cells should be regarded not only as victims in the context of chronic kidney disease, but also as actors playing an ambiguous role. In particular, we report on studies which demonstrated that they can actively contribute to fibrogenesis itself, either directly, because their function has been reprogrammed in a way reminiscent of their mesenchymal origin, or from a distance, by influencing endothelial and myofibroblast functions. Last, they are seen as potential targets for new drugs aiming at controlling fibrosis.
Publish Date	2015-07-06 18:45
Citation	Louis K, Hertig A. How tubular epithelial cells dictate the rate of renal fibrogenesis? World J Nephrol 2015; 4(3): 367-373
URL	http://www.wjgnet.com/2220-6124/full/v4/i3/367.htm
DOI	http://dx.doi.org/10.5527/wjn.v4.i3.367

Full Article (PDF)	WJN-4-367.pdf
Full Article (Word)	WJN-4-367.doc
Manuscript File	17073-Review.doc
Answering Reviewers	17073-Answering reviewers.pdf
Audio Core Tip	17073-Audio core tip.wav
Conflict-of-Interest Disclosure Form	17073-Conflict-of-interest statement.pdf
Copyright License Agreement	17073-Copyright assignment.pdf
Peer-review Report	17073-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	17073-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	17073-Scientific misconduct check.pdf
Scientific Editor Work List	17073-Scientific editor work list.pdf