Publication Name	World Journal of Orthopedics
Manuscript ID	17105
Country	Canada

Received	2015-02-12 09:24
Peer-Review Started	2015-02-12 10:31
To Make the First Decision	2015-04-10 17:20
Return for Revision	2015-04-15 11:10
Revised	2015-05-02 08:42
Second Decision	2015-05-25 12:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-06-02 17:26
Articles in Press	2015-06-02 17:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-30 18:47
Publish the Manuscript Online	2015-07-14 18:18

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Use of Teriparatide to improve fracture healing: What is the evidence?
Manuscript Source	Invited Manuscript
All Author List	Satish Babu, Nemandra A Sandiford and Mark Vrahas
Funding Agency and Grant Number
Corresponding Author	Nemandra A Sandiford, FRCS (Trauma and Orthopaedics), Lower Limb and Tumor Reconstruction Fellow, University of British Columbia, 2329 West Mall, Vancouver V5Z 1M9, British Columbia, Canada. nemsandiford@hotmail.com
Key Words	Teriparatide; Fractures; Healing; Bone; Osteoporosis
Core Tip	Teriparatide contains the biologically active component of Parathyroid Hormone. It is utilised in osteoporosis for its ability to increase bone mass and prevent fractures. Research suggests Teriparatide may improve callus volume, callus mineralisation, bone mineral content and successful union. However most research come from animal models. Human research, whilst supporting Teriparatide use, mostly comprises low level evidence such as case series. Currently many United States physicians use Teriparatide “off license” for fractures and non-unions. We suggest more, well designed, human randomised controlled trials are required before Teriparatide can become a mainstream option in the conservative management of fractures and non-unions.
Publish Date	2015-07-14 18:18
Citation	Babu S, Sandiford NA, Vrahas M. Use of Teriparatide to improve fracture healing: What is the evidence? World J Orthop 2015; 6(6): 457-461
URL	http://www.wjgnet.com/2218-5836/full/v6/i6/457.htm
DOI	http://dx.doi.org/10.5312/wjo.v6.i6.457

Full Article (PDF)	WJO-6-457.pdf
Full Article (Word)	WJO-6-457.doc
Manuscript File	17105-Review.docx
Answering Reviewers	17105-Answering reviewers.pdf
Audio Core Tip	17105-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	17105-Conflict-of-interest statement.pdf
Copyright License Agreement	17105-Copyright assignment.pdf
Peer-review Report	17105-Peer-review(s).pdf
Scientific Misconduct Check	17105-Scientific misconduct check.pdf
Scientific Editor Work List	17105-Scientific editor work list.pdf