Publication Name	World Journal of Gastroenterology
Manuscript ID	17160
Country

Received	2015-02-21 21:41
Peer-Review Started	2015-02-23 10:03
To Make the First Decision	2015-03-26 16:31
Return for Revision	2015-04-01 13:58
Revised	2015-05-01 11:29
Second Decision	2015-05-20 07:52
Accepted by Journal Editor-in-Chief	2015-05-22 06:27
Accepted by Company Editor-in-Chief	2015-05-27 19:52
Articles in Press	2015-05-27 19:53
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-06-29 16:01
Typeset the Manuscript	2015-07-15 17:25
Publish the Manuscript Online	2015-08-08 15:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Basic Study
Article Title	Overexpression of pim-3 and protective role in lipopolysaccharide-stimulated hepatic stellate cells
Manuscript Source	Unsolicited Manuscript
All Author List	Lin-Hua Liu, Qi-Nan Lai, Jian-Yong Chen, Ji-Xiang Zhang and Bin Cheng
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81360074
Corresponding Author	Ji-Xiang Zhang, MD, Department of Gastroenterology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang 330006, Jiangxi Province, China. jixiangz@tom.com
Key Words	Pim-3; Lipopolysaccharide; Hepatic stellate cell; Si-pim3
Core Tip	Hepatic stellate cell (HSC)-T6 cells stimulated by lipopolysaccharide (LPS) showed overexpression of pim-3 kinase. Overexpression of pim-3 in LPS-stimulated HSC-T6 cells protected against apoptosis and promoted proliferation. Knockdown of pim3 gene abolished proliferation of HSC-T6 cells and led to apoptosis. Overexpression of pim-3 induced by LPS play a protective role in rat hepatic stellate cells.
Publish Date	2015-08-08 15:26
Citation	Liu LH, Lai QN, Chen JY, Zhang JX, Cheng B. Overexpression of pim-3 and protective role in lipopolysaccharide-stimulated hepatic stellate cells. World J Gastroenterol 2015; 21(29): 8858-8867
URL	http://www.wjgnet.com/1007-9327/full/v21/i29/8858.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i29.8858

Full Article (PDF)	WJG-21-8858.pdf
Full Article (Word)	WJG-21-8858.doc
Manuscript File	17160-Review.doc
Answering Reviewers	17160-Answering reviewers.pdf
Audio Core Tip	17160-Audio core tip.mp3
Biostatistics Review Certificate	17160-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	17160-Conflict-of-interest statement.pdf
Copyright License Agreement	17160-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	17160-Institutional animal care and use committee statement.pdf
Peer-review Report	17160-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	17160-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	17160-Scientific misconduct check.pdf
Scientific Editor Work List	17160-Scientific editor work list.pdf