Publication Name	World Journal of Gastroenterology
Manuscript ID	17207
Country	Japan

Received	2015-02-25 10:44
Peer-Review Started	2015-02-26 14:22
To Make the First Decision	2015-04-23 13:14
Return for Revision	2015-04-30 15:58
Revised	2015-05-18 20:31
Second Decision	2015-06-23 18:22
Accepted by Journal Editor-in-Chief	2015-06-23 19:31
Accepted by Executive Editor-in-Chief	2015-06-26 15:07
Articles in Press	2015-06-26 15:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-16 16:09
Publish the Manuscript Online	2015-08-08 15:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Clinical applications of 5-aminolevulinic acid-mediated fluorescence for gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Tsutomu Namikawa, Tomoaki Yatabe, Keiji Inoue, Taro Shuin and Kazuhiro Hanazaki
Funding Agency and Grant Number
Corresponding Author	Tsutomu Namikawa, MD, Department of Surgery, Kochi Medical School, Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan. tsutomun@kochi-u.ac.jp
Key Words	Fluorescence imaging; 5-aminolevulinic acid; Photodynamic diagnosis; Photodynamic therapy; Gastric cancer
Core Tip	5-Aminolevulinic acid (ALA) is a naturally occurring amino acid that is a protoporphyrin IX precursor and a next-generation photosensitive substance. Fluorescence navigation by photodynamic diagnosis (PDD) using ALA is a potentially valuable diagnostic tool for gastric cancer for evaluating both the surgical resection margins and the extension of the lesion. Furthermore, PDD using ALA might be useful to detect peritoneal metastases during preoperative staging laparoscopy and evaluation of lymph node metastases. Photodynamic therapy using ALA to cause selective damage based on the accumulation of a photosensitizer in malignant tissue is expected to become a non-invasive endoscopic treatment for superficial early gastric cancer.
Publish Date	2015-08-08 15:26
Citation	Namikawa T, Yatabe T, Inoue K, Shuin T, Hanazaki K. Clinical applications of 5-aminolevulinic acid-mediated fluorescence for gastric cancer. World J Gastroenterol 2015; 21(29): 8769-8775
URL	http://www.wjgnet.com/1007-9327/full/v21/i29/8769.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i29.8769

Full Article (PDF)	WJG-21-8769.pdf
Full Article (Word)	WJG-21-8769.doc
Manuscript File	17207-Review.docx
Answering Reviewers	17207-Answering reviewers.pdf
Audio Core Tip	17207-Audio core tip.wav
Conflict-of-Interest Disclosure Form	17207-Conflict-of-interest statement.pdf
Copyright License Agreement	17207-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	17207-Language certificate.pdf
Peer-review Report	17207-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	17207-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	17207-Scientific misconduct check.pdf
Scientific Editor Work List	17207-Scientific editor work list.pdf