Publication Name	World Journal of Orthopedics
Manuscript ID	17407
Country	Greece

Received	2015-03-05 08:24
Peer-Review Started	2015-03-08 19:30
To Make the First Decision	2015-04-10 17:23
Return for Revision	2015-04-15 11:44
Revised	2015-04-25 23:59
Second Decision	2015-05-25 12:03
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-06-02 17:37
Articles in Press	2015-06-02 17:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-04 20:31
Publish the Manuscript Online	2015-08-20 08:24

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Systematic Reviews
Article Title	Persistent post-surgical pain and neuropathic pain after total knee replacement
Manuscript Source	Invited Manuscript
All Author List	Georgios I Drosos, Triantafilia Triantafilidou, Athanasios Ververidis, Cristina Agelopoulou, Theodosia Vogiatzaki and Konstantinos Kazakos
Funding Agency and Grant Number
Corresponding Author	Georgios I Drosos, MD, PhD, Assistant Professor, Department of Orthopaedic Surgery, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Dragana, 68100 Alexandroupolis, Greece. drosos@otenet.gr
Key Words	Total knee replacement; Pain; Chronic pain; Neuropathic pain; Post-operative pain; Persistent post-surgical pain
Core Tip	Persistent post-surgical pain (PPSP) is reported in a significant proportion of patients after total knee replacement. This proportion varies between the different studies and different factors have been implicated including the instrument used to measure pain. It is also obvious that in some of these patients the pain is neuropathic (NP) in origin or the NP pain coexists. Nevertheless, due to the heterogeneity of the studies, mainly on the scales used to assess pain and preoperative factors, we are unable to reach firm conclusions concerning the prevalence, and the risk factors of PPSP pain after total knee replacement. Additional studies focused on the prevalence and risk factors related to PPSP are needed.
Publish Date	2015-08-20 08:24
Citation	Drosos GI, Triantafilidou T, Ververidis A, Agelopoulou C, Vogiatzaki T, Kazakos K. Persistent post-surgical pain and neuropathic pain after total knee replacement. World J Orthop 2015; 6(7): 528-536
URL	http://www.wjgnet.com/2218-5836/full/v6/i7/528.htm
DOI	http://dx.doi.org/10.5312/wjo.v6.i7.528

Full Article (PDF)	WJO-6-528.pdf
Full Article (Word)	WJO-6-528.doc
Manuscript File	17407-Review.doc
Answering Reviewers	17407-Answering reviewers.pdf
Audio Core Tip	17407-Audio core tip.wav
Biostatistics Review Certificate	17407-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	17407-Conflict-of-interest statement.pdf
Copyright License Agreement	17407-Copyright assignment.pdf
Peer-review Report	17407-Peer-review(s).pdf
Scientific Misconduct Check	17407-Scientific misconduct check.pdf
Scientific Editor Work List	17407-Scientific editor work list.pdf