Publication Name	World Journal of Biological Chemistry
Manuscript ID	17408
Country	Malaysia

Received	2015-03-05 16:18
Peer-Review Started	2015-03-07 14:11
To Make the First Decision	2015-04-27 15:48
Return for Revision	2015-04-28 17:38
Revised	2015-05-05 14:27
Second Decision	2015-06-24 08:22
Accepted by Journal Editor-in-Chief	2015-06-24 17:26
Accepted by Executive Editor-in-Chief	2015-07-02 16:17
Articles in Press	2015-07-02 16:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-08 16:35
Publish the Manuscript Online	2015-08-26 11:07

ISSN	1949-8454 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Biotechnology & Applied Microbiology
Manuscript Type	Basic Study
Article Title	Effect of agitation speed on the morphology of Aspergillus niger HFD5A-1 hyphae and its pectinase production in submerged fermentation
Manuscript Source	Invited Manuscript
All Author List	Darah Ibrahim, Haritharan Weloosamy and Sheh-Hong Lim
Funding Agency and Grant Number	Funding Agency Grant Number Universiti Sains Malaysia Scientific Research Fund
Corresponding Author	Sheh-Hong Lim, PhD, Researcher, Industrial Biotechnology Research Laboratory, School of Biological Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia. limshehhong77@gmail.com
Key Words	Aspergillus niger; Agitation; Submerged culture; Pectinase; Microbial growth; Dissolved oxygen
Core Tip	We report the influence of agitation speed on pectinase production on our newly isolate Aspergillus niger (A. niger) HFM5A-1 in submerged fermentation. The agitation speed was found to influence pectinase production in a batch cultivation system. However, higher agitation speeds than the optimal speed (150 rpm) reduced pectinase production which due to shear forces and also collision among the suspended fungal cells in the cultivation medium. It was found that agitation speed affected the morphological characteristics of the fungal hyphae/mycelia of A. niger HFD5A-1 by altering their external as well as internal cell structures.
Publish Date	2015-08-26 11:07
Citation	Ibrahim D, Weloosamy H, Lim SH. Effect of agitation speed on the morphology of Aspergillus niger HFD5A-1 hyphae and its pectinase production in submerged fermentation. World J Biol Chem 2015; 6(3): 265-271
URL	http://www.wjgnet.com/1949-8454/full/v6/i3/265.htm
DOI	http://dx.doi.org/10.4331/wjbc.v6.i3.265

Full Article (PDF)	WJBC-6-265.pdf
Full Article (Word)	WJBC-6-265.doc
Manuscript File	17408-Review.docx
Answering Reviewers	17408-Answering reviewers.pdf
Audio Core Tip	17408-Audio core tip.mp3
Biostatistics Review Certificate	17408-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	17408-Conflict-of-interest statement.pdf
Copyright License Agreement	17408-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	17408-Institutional review board statement.pdf
Peer-review Report	17408-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	17408-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	17408-Scientific misconduct check.pdf
Scientific Editor Work List	17408-Scientific editor work list.pdf