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Articles Published Processes
12/10/2015 10:17:00 AM | Browse: 1459 | Download: 2940
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Received |
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2015-03-08 14:50 |
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Peer-Review Started |
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2015-03-11 18:01 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2015-04-29 17:56 |
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Revised |
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2015-05-25 07:05 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2015-08-10 08:15 |
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Second Decision by Editor-in-Chief |
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2015-08-10 16:15 |
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Final Decision by Editorial Office Director |
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2015-08-31 13:30 |
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Articles in Press |
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2015-08-31 13:30 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-09-28 11:43 |
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Publish the Manuscript Online |
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2015-10-19 09:14 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Low-density lipoprotein receptor genetic polymorphism in chronic hepatitis C virus Egyptian patients affects treatment response
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mazen Naga, Mona Amin, Dina Algendy, Ahmed Elbadry, May Fawzi, Ayman Foda, Serag Esmat, Dina Sabry, Laila Rashed, Samia Gabal and Manal Kamal |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Development Fund, Ministry of Scientific Research Egypt |
1587 |
| Cairo University |
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| Corresponding Author |
Mona Amin, Professor, Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11562,
Egypt. monasleman@hotmail.com |
| Key Words |
Hepatitis C virus; Genetic polymorphisms; Low-density lipoprotein receptor; Egypt; Hepatitis C virus response to treatment |
| Core Tip |
Two molecules may function as hepatitis C virus (HCV) receptors, namely the low density lipoprotein receptor (LDLR) and CD81. This work asse-ssed the role of genetic polymorphisms of the LDLR in Egyptian chronic HCV patients and its cor-relation with antiviral responses to treatment with pegylated interferon /ribavirin therapy. The study demonstrated that LDLR gene polymorphisms play a role in the response to viral treatment. The G allele of LDLRs exon8c.1171G>A predominated in cases and controls over the A allele. Carriers of the A allele exhibited a 16.4 times greater risk for non-response. |
| Publish Date |
2015-10-19 09:14 |
| Citation |
Naga M, Amin M, Algendy D, Elbadry A, Fawzi M, Foda A, Esmat S, Sabry D, Rashed L, Gabal S, Kamal M. Low-density lipoprotein receptor genetic polymorphism in chronic hepatitis C virus Egyptian patients affects treatment response. World J Gastroenterol 2015; 21(39): 11141-11151 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i39/11141.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i39.11141 |
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