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12/10/2015 10:17:00 AM | Browse: 1142 | Download: 1767
Publication Name World Journal of Gastroenterology
Manuscript ID 17452
Country/Territory Egypt
Received
2015-03-08 14:50
Peer-Review Started
2015-03-11 18:01
To Make the First Decision
2015-04-24 19:21
Return for Revision
2015-04-29 17:56
Revised
2015-05-25 07:05
Second Decision
2015-08-10 08:15
Accepted by Journal Editor-in-Chief
2015-08-10 16:15
Accepted by Company Editor-in-Chief
2015-08-31 13:30
Articles in Press
2015-08-31 13:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-09-28 11:43
Publish the Manuscript Online
2015-10-19 09:14
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Control Study
Article Title Low-density lipoprotein receptor genetic polymorphism in chronic hepatitis C virus Egyptian patients affects treatment response
Manuscript Source Unsolicited Manuscript
All Author List Mazen Naga, Mona Amin, Dina Algendy, Ahmed Elbadry, May Fawzi, Ayman Foda, Serag Esmat, Dina Sabry, Laila Rashed, Samia Gabal and Manal Kamal
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Development Fund, Ministry of Scientific Research Egypt 1587
Cairo University
Corresponding Author Mona Amin, Professor, Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11562, Egypt. monasleman@hotmail.com
Key Words Hepatitis C virus; Genetic polymorphisms; Low-density lipoprotein receptor; Egypt; Hepatitis C virus response to treatment
Core Tip Two molecules may function as hepatitis C virus (HCV) receptors, namely the low density lipoprotein receptor (LDLR) and CD81. This work asse-ssed the role of genetic polymorphisms of the LDLR in Egyptian chronic HCV patients and its cor-relation with antiviral responses to treatment with pegylated interferon /ribavirin therapy. The study demonstrated that LDLR gene polymorphisms play a role in the response to viral treatment. The G allele of LDLRs exon8c.1171G>A predominated in cases and controls over the A allele. Carriers of the A allele exhibited a 16.4 times greater risk for non-response.
Publish Date 2015-10-19 09:14
Citation Naga M, Amin M, Algendy D, Elbadry A, Fawzi M, Foda A, Esmat S, Sabry D, Rashed L, Gabal S, Kamal M. Low-density lipoprotein receptor genetic polymorphism in chronic hepatitis C virus Egyptian patients affects treatment response. World J Gastroenterol 2015; 21(39): 11141-11151
URL http://www.wjgnet.com/1007-9327/full/v21/i39/11141.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i39.11141
Full Article (PDF) WJG-21-11141.pdf
Full Article (Word) WJG-21-11141.doc
Manuscript File 17452-Review.doc
Answering Reviewers 17452-Answering reviewers.pdf
Audio Core Tip 17452-Audio core tip.mp3
Biostatistics Review Certificate 17452-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 17452-Conflict of intrest statment.pdf
Copyright License Agreement 17452-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 17452-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 17452-Language certificate.pdf
Peer-review Report 17452-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 17413-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 17452-Scientific misconduct check.pdf
Scientific Editor Work List 17452-Scientific editor work list.pdf