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Articles Published Processes
7/8/2015 12:00:00 PM | Browse: 1076 | Download: 2160
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Received |
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2015-03-12 09:16 |
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Peer-Review Started |
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2015-03-13 08:54 |
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To Make the First Decision |
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2015-03-26 16:53 |
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Return for Revision |
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2015-04-01 14:28 |
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Revised |
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2015-04-23 06:44 |
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Second Decision |
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2015-05-04 08:23 |
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Accepted by Journal Editor-in-Chief |
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2015-05-04 14:55 |
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Accepted by Executive Editor-in-Chief |
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2015-05-07 16:03 |
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Articles in Press |
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2015-05-07 16:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-05-25 04:39 |
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Typeset the Manuscript |
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2015-06-17 09:53 |
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Publish the Manuscript Online |
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2015-07-08 12:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
NOD2/CARD15 gene mutations in North Algerian patients with inflammatory bowel disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Aziza Boukercha, Hamida Mesbah-Amroun, Amira Bouzidi, Houria Saoula, Mhamed Nakkemouche, Maryline Roy, Jean-Pierre Hugot and Chafia Touil-Boukoffa |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Agence Thématique de la Recherche Scientifique en Santé |
PNR N°37-ANDRS-2011 |
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| Corresponding Author |
Hamida Mesbah-Amroun, PhD, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Sciences and Technology Houari Boumediene, BP32, Bab-Ezzouar, Algiers 16111, Algeria. amrounhamida@yahoo.com |
| Key Words |
Algeria; Crohn’s disease; Ulcerative colitis; Inflammatory bowel disease; NOD2 mutations; Polymerase chain reaction-restriction fragment length polymorphism method |
| Core Tip |
We evaluated allelic frequency of NOD2 variants among 132 inflammatory bowel disease (IBD) patients and 114 unrelated healthy subjects from Algeria. Despite the fact that the frequency of NOD2 mutant alleles is in the range found in most of the European populations, we failed to demonstrate the association of these NOD2 variants with IBD susceptibility. This might be due to the non exposure of the NOD2 carriers to environmental factors, required for the expression of the disease. We can expect in the coming years to see an increased incidence of IBD associated with the spread of Western lifestyle in this region. |
| Publish Date |
2015-07-08 12:01 |
| Citation |
Boukercha A, Mesbah-Amroun H, Bouzidi A, Saoula H, Nakkemouche M, Roy M, Hugot JP, Touil-Boukoffa C. NOD2/CARD15 gene mutations in North Algerian patients with inflammatory bowel disease. World J Gastroenterol 2015; 21(25): 7786-7794 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i25/7786.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i25.7786 |
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