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7/14/2015 12:20:00 PM | Browse: 607 | Download: 1117
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 17667
Country of Manuscript Source India
2015-03-18 09:31
Peer-Review Started
2015-03-21 20:23
To Make the First Decision
2015-04-10 17:29
Return for Revision
2015-04-15 13:26
2015-05-14 23:51
Second Decision
2015-05-25 12:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-06-02 17:41
Articles in Press
2015-06-02 17:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-07-02 10:58
Publish the Manuscript Online
2015-07-14 12:20
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Case Control Study
Article Title Association of endothelial nitric oxide synthase gene T-786C promoter polymorphism with gastric cancer
Manuscript Source Invited Manuscript
All Author List Devulapalli Krishnaveni, Bhayal Amar Chand, Porika Shravan Kumar, Malladi Uma Devi, Macherla Ramanna, Akka Jyothy, Nallari Pratibha, N Balakrishna and Ananthapur Venkateshwari
Funding Agency and Grant Number
Corresponding author Dr. Ananthapur Venkateshwari, Assistant Professor, Department of Cell Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India. venkateshwari@yahoo.com
Keywords Genetics; Helicobacter pylori; Nutrition; Oncology; Endoscopy; Gastro duodenal; Nitric oxide; Single nucleotide polymorphism rs2070744; Agarose gel electrophoresis; Allele specific polymerase chain reaction
Core Tip The present study reveals first molecular epidemiological evidence from south Indian cohort for the association of endothelial nitric oxide synthase -786T > C promoter polymorphism with a risk to develop gastric cancer (GC). The CC genotype and C allele of the -786T > C polymorphism were significantly associated with an elevated risk to GC, probably due to the lowered nitric oxide levels in case of C/C genotype which result in tumour proliferation, angiogenesis and metastasis.
Publish Date 2015-07-14 12:20
Citation Krishnaveni D, Amar Chand B, Shravan Kumar P, Uma Devi M, Ramanna M, Jyothy A, Pratibha N, Balakrishna N, Venkateshwari A. Association of endothelial nitric oxide synthase gene T-786C promoter polymorphism with gastric cancer. World J Gastrointest Oncol 2015; 7(7): 87-94
Url http://www.wjgnet.com/1948-5204/full/v7/i7/87.htm
DOI http://dx.doi.org/10.4251/wjgo.v7.i7.87
Full Article (PDF) WJGO-7-87.pdf
Full Article (Word) WJGO-7-87.doc
Manuscript File 17667-Review.docx
Answering Reviewers 17667-Answering reviewers.pdf
Audio Core Tip 17667-Audio core tip.MP3
Biostatistics Review Certificate 17667-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 17667-Conflict-of-interest statement.pdf
Copyright License Agreement 17667-Copyright assignment.pdf
Data Sharing Statement 17667-Data sharing statement.PDF
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20150317204106.docx
Institutional Review Board Approval Form or Document 17667-Institutional review board statement.PDF
Peer-review Report 17667-Peer-review(s).pdf
Scientific Misconduct Check 17667-Scientific misconduct check.pdf
Scientific Editor Work List 17667-Scientific editor work list.pdf