| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Alpha-fetoprotein before and after pegylated interferon therapy for predicting hepatocellular carcinoma development
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yasuto Takeuchi, Fusao Ikeda, Toshiya Osawa, Yasuyuki Araki, Kouichi Takaguchi, Youichi Morimoto, Noriaki Hashimoto, Kousaku Sakaguchi, Tatsuro Sakata, Masaharu Ando, Yasuhiro Makino, Shuji Matsumura, Hiroki Takayama, Hiroyuki Seki, Shintarou Nanba, Yuki Moritou, Tetsuya Yasunaka, Hideki Ohnishi, Akinobu Takaki, Kazuhiro Nouso, Yoshiaki Iwasaki and Kazuhide Yamamoto |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| In part a Research Program for Intractable Disease by the Ministry of Health, Labor, and Welfare of Japan |
to Iwasaki Y |
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| Corresponding Author |
Fusao Ikeda, MD, Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8558,
Japan. fikeda@md.okayama-u.ac.jp
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| Key Words |
Hepatitis C virus; Interferon; Hepatocellular carcinoma; Alpha-fetoprotein |
| Core Tip |
What is current knowledge: (1) Alpha-fetoprotein (AFP) values can predict development of hepatocellular carcinoma (HCC) after interferon therapy in patients with hepatitis C virus; and (2) The predictive value of AFP on HCC development after interferon therapy and its criteria remained uncertain. What is new here: AFP values before interferon therapy have strong predictive value on HCC development after interferon therapy. The simple criteria defined by AFP values before and 1 year after interferon therapy might work efficient to predict HCC development after interferon therapy.
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| Publish Date |
2015-09-09 14:44 |
| Citation |
Takeuchi Y, Ikeda F, Osawa T, Araki Y, Takaguchi K, Morimoto Y, Hashimoto N, Sakaguchi K, Sakata T, Ando M, Makino Y, Matsumura S, Takayama H, Seki H, Nanba S, Moritou Y, Yasunaka T, Ohnishi H, Takaki A, Nouso K, Iwasaki Y, Yamamoto K. Alpha-fetoprotein before and after pegylated interferon therapy for predicting hepatocellular carcinoma development. World J Hepatol 2015; 7(19): 2220-2228 |
| URL |
http://www.wjgnet.com/1948-5182/full/v7/i19/2220.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v7.i19.2220 |
