Publication Name	World Journal of Clinical Cases
Manuscript ID	17764
Country

Received	2015-03-23 09:32
Peer-Review Started	2015-03-25 19:23
To Make the First Decision	2015-04-10 17:40
Return for Revision	2015-04-17 10:34
Revised	2015-04-21 08:06
Second Decision	2015-05-29 15:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-06-08 16:07
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-27 17:36
Publish the Manuscript Online	2015-09-15 18:41

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Case Report
Article Title	Horseshoe thrombus in a patient with mechanical prosthetic mitral valve: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Sanjay Mehra, Assad Movahed, Carlos Espinoza and Constantin B Marcu
Funding Agency and Grant Number
Corresponding Author	Assad Movahed, MD, FACC, FACP, Department of Cardiovascular Sciences, East Carolina University, 115 Heart Drive, Greenville, NC 27834, United States. movaheda@ecu.edu
Key Words	Thrombosis; Anticoagulation; Thrombolytic therapy; Transthoracic echocardiogram; Prosthetic valves; Transesophageal echocardiogram
Core Tip	Patients with mechanical prosthetic cardiac valves require life long systemic anticoagulation. Maintaining therapeutic anticoagulation consistently is challenging, given the variable dose requirements with warfarin, especially with dietary changes and drug interactions. We present a case of a patient with fluctuating control of anticoagulation, which led to an unusually large horseshoe thrombus in her left atrium and subsequent cerebrovascular complications. We also provide a review of literature, diagnostic modalities and treatment options.
Publish Date	2015-09-15 18:41
Citation	Mehra S, Movahed A, Espinoza C, Marcu CB. Horseshoe thrombus in a patient with mechanical prosthetic mitral valve: A case report and review of literature. World J Clin Cases 2015; 3(9): 838-842
URL	http://www.wjgnet.com/2307-8960/full/v3/i9/838.htm
DOI	http://dx.doi.org/10.12998/wjcc.v3.i9.838

Full Article (PDF)	WJCC-3-838.pdf
Full Article (Word)	WJCC-3-838.doc
Manuscript File	17764-Review.doc
Answering Reviewers	17764-Answering reviewers.pdf
Audio Core Tip	17764-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	17764-Conflict-of-interest statement.pdf
Copyright License Agreement	17764-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	17764-Institutional review board statement.pdf
Peer-review Report	17764-Peer-review(s).pdf
Scientific Misconduct Check	17764-Scientific misconduct check.pdf
Scientific Editor Work List	17764-Scientific editor work list.pdf