Publication Name	World Journal of Hepatology
Manuscript ID	17781
Country	Singapore

Received	2015-03-25 17:10
Peer-Review Started	2015-03-26 18:37
To Make the First Decision	2015-05-13 19:49
Return for Revision	2015-05-18 19:59
Revised	2015-08-25 00:01
Second Decision	2015-10-13 08:51
Accepted by Journal Editor-in-Chief	2015-10-13 09:52
Accepted by Executive Editor-in-Chief	2015-10-27 17:47
Articles in Press	2015-10-27 17:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-23 12:19
Publish the Manuscript Online	2015-11-27 17:14

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Surgery
Manuscript Type	Systematic Reviews
Article Title	Comparative study and systematic review of laparoscopic liver resection for hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Wei Qi Leong, Iyer Shridhar Ganpathi, Alfred Wei Chieh Kow, Krishnakumar Madhavan and Stephen Kin Yong Chang
Funding Agency and Grant Number
Corresponding Author	Stephen Kin Yong Chang, Associate Professor, Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, National University Health System, 1E Kent Ridge Road, NUHS Tower Block, Level 8, Singapore 119228, Singapore. cfscky@nus.edu.sg
Key Words	Hepatocellular carcinoma; Laparoscopy; Open liver resection; Hepatectomy; Surgery
Core Tip	Surgical resection is the standard treatment for hepatocellular carcinoma (HCC), and provides the best outcomes for patients eligible for resection. Laparoscopic liver resection (LLR) is a relatively new advancement in treatment of HCC and has raised concerns on its feasibility and safety. We reviewed 17 studies and performed our own comparative study on surgical outcomes of LLR vs open liver resection for the curative treatment of HCC. We showed that LLR resulted in more desirable short-term outcomes, whereas long-term oncologic outcomes were comparable. Hence, LLR is a safe and feasible option in the surgical treatment of HCC.
Publish Date	2015-11-27 17:14
Citation	Leong WQ, Ganpathi IS, Kow AWC, Madhavan K, Chang SKY. Comparative study and systematic review of laparoscopic liver resection for hepatocellular carcinoma. World J Hepatol 2015; 7(27): 2765-2773
URL	http://www.wjgnet.com/1948-5182/full/v7/i27/2765.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i27.2765

Full Article (PDF)	WJH-7-2765.pdf
Full Article (Word)	WJH-7-2765.doc
Manuscript File	17781-Review.docx
Answering Reviewers	17781-Answering reviewers.pdf
Audio Core Tip	17781-Audio core tip.mp3
Biostatistics Review Certificate	17781-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	17781-Conflict-of-interest statement.pdf
Copyright License Agreement	17781-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Institutional_Review_Board_Statement_20150323233624.pdf
Peer-review Report	17781-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	17781-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	17781-Scientific misconduct check.pdf
Scientific Editor Work List	17781-Scientific editor work list.pdf