BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/20/2015 1:37:00 PM | Browse: 997 | Download: 2843
 |
Received |
|
2015-03-27 17:15 |
|
Peer-Review Started |
|
2015-03-28 18:48 |
|
To Make the First Decision |
|
2015-06-02 13:29 |
|
Return for Revision |
|
2015-06-06 15:04 |
|
Revised |
|
2015-06-22 08:52 |
|
Second Decision |
|
2015-06-26 09:47 |
|
Accepted by Journal Editor-in-Chief |
|
2015-06-29 15:29 |
|
Accepted by Executive Editor-in-Chief |
|
2015-07-03 17:01 |
|
Articles in Press |
|
2015-07-03 17:01 |
 |
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2015-08-05 14:49 |
|
Publish the Manuscript Online |
|
2015-08-20 13:37 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pathology |
| Manuscript Type |
Basic Study |
| Article Title |
Influence of the hTERT rs2736100 polymorphism on telomere length in gastric cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Byung Joon Choi, Jung Hwan Yoon, Olga Kim, Won Suk Choi, Suk Woo Nam, Jung Young Lee and Won Sang Park |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Basic Science Research Programs |
2012R1A2A2A01002531 |
|
| Corresponding Author |
Won Sang Park, MD, PhD, Professor of Medicine, Department of Pathology, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Seocho-gu, Seoul 137-701, South Korea. wonsang@catholic.ac.kr |
| Key Words |
Human telomerase reverse transcriptase; Telomere; Gastric cancer; Polymorphism; Risk |
| Core Tip |
The rs2736100 polymorphism is closely associated with reduced human telomerase reverse transcriptase (hTERT) mRNA expression and shortened telomere length in gastric cancer tissue and cell lines. Additionally, telomere length and hTERT mRNA levels were significantly increased in those with the C/C genotype in intestinal-type gastric cancer. Notably, there was no significant difference in the genotype and allele frequencies of the rs2736100 polymorphism between the patients with gastric cancer and healthy controls. These results suggest that the rs2736100 polymorphism of the hTERT gene is involved in the regulation of hTERT expression and telomere length, but not in the risk of gastric cancer. |
| Publish Date |
2015-08-20 13:37 |
| Citation |
Choi BJ, Yoon JH, Kim O, Choi WS, Nam SW, Lee JY, Park WS. Influence of the hTERT rs2736100 polymorphism on telomere length in gastric cancer. World J Gastroenterol 2015; 21(31): 9328-9336 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i31/9328.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i31.9328 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
