Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	17928
Country	Egypt

Received	2015-03-30 17:16
Peer-Review Started	2015-03-31 20:42
To Make the First Decision	2015-06-03 14:17
Return for Revision	2015-06-09 09:17
Revised	2015-07-11 02:12
Second Decision	2015-08-13 17:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-08-21 16:22
Articles in Press	2015-08-21 16:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-22 16:10
Publish the Manuscript Online	2015-11-10 12:29

ISSN	2219-2808 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	Apnea; Caffeine; Preterm; Methylxanthines
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Review
Article Title	Caffeine therapy in preterm infants
Manuscript Source	Invited Manuscript
All Author List	Hesham Abdel-Hady, Nehad Nasef, Abd Elazeez Shabaan and Islam Nour
Funding Agency and Grant Number
Corresponding Author	Hesham Abdel-Hady, Professor of Pediatrics and Neonatology, Neonatal Intensive Care Unit, Mansoura University Children’s Hospital, Gomhoria street, Mansoura 35516, Egypt. hehady@yahoo.com
Key Words	Apnea; Caffeine; Preterm; Methylxanthines
Core Tip	Caffeine is among the most commonly prescribed medications in neonatal intensive care units, it has now largely replaced other methylxanthines. Caffeine reduces the frequency of apnea, intermittent hypoxemia, facilitates extubation from mechanical ventilation, and reduces the incidence of bronchopulmonary and patent ductus arteriosus in preterm infants. There are controversies regarding the safety and efficacy of high-dose, early vs late administration, duration of therapy, value in older gestational age infants and the value of therapeutic drug monitoring.
Publish Date	2015-11-10 12:29
Citation	Abdel-Hady H, Nasef N, Shabaan AE, Nour I. Caffeine therapy in preterm infants. World J Clin Pediatr 2015; 4(4): 81-93
URL	http://www.wjgnet.com/2219-2808/full/v4/i4/81.htm
DOI	http://dx.doi.org/10.5409/wjcp.v4.i4.81

Full Article (PDF)	WJCP-4-81.pdf
Full Article (Word)	WJCP-4-81.doc
Manuscript File	17928-Review.doc
Answering Reviewers	17928-Answering reviewers.pdf
Audio Core Tip	17928-Audio Core tip.mp3
Conflict-of-Interest Disclosure Form	17928-Conflict of interest statement.pdf
Copyright License Agreement	17928-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	17928-Language certificate.pdf
Peer-review Report	17928-Peer-review(s).pdf
Scientific Misconduct Check	17928-Scientific misconduct check.pdf
Scientific Editor Work List	17928-Scientific editor work list.pdf