Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	17942
Country	Thailand

Received	2015-03-31 08:02
Peer-Review Started	2015-03-31 17:20
To Make the First Decision	2015-06-03 14:17
Return for Revision	2015-06-09 09:21
Revised	2015-06-11 00:52
Second Decision	2015-07-09 08:35
Accepted by Journal Editor-in-Chief	2015-07-09 22:24
Accepted by Executive Editor-in-Chief	2015-07-23 16:42
Articles in Press	2015-07-23 16:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-27 15:26
Publish the Manuscript Online	2015-08-08 13:26

ISSN	2150-5349 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Current position of vasoconstrictor and albumin infusion for type 1 hepatorenal syndrome
Manuscript Source	Invited Manuscript
All Author List	Abhasnee Sobhonslidsuk
Funding Agency and Grant Number
Corresponding Author	Abhasnee Sobhonslidsuk, MD, Associate Professor, Division of Gastroenterology and Hepatology, Depart­ment of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama 6 road, Rajathevee, Bangkok 10400, Thailand. abhasnee.sob@mahidol.ac.th
Key Words	Albumin; Acute kidney injury; Hepatorenal syndrome; Cirrhosis; Vasoconstrictor
Core Tip	Type 1 hepatorenal syndrome (HRS), which presents as acute kidney injury, is an uncommon, but critical problem in decompensated cirrhosis. The most common precipitating factor is infection especially spontaneous bacterial peritonitis. The combined regimen of albumin and vasoconstrictor is the pharmacotherapy of choice for type 1 HRS based on pathogenic me-chanisms of peripheral and splanchnic vasodilatation. Prompt treatment with the combined regimen can lead to HRS reversal in 34%-60% of patients. Type 1 HRS can be prevented in cirrhotic complications such as albumin infusion for spontaneous bacterial peritonitis, large volume paracentesis with albumin replacement, and prophylactic antibiotics for upper gastrointestinal hemorrhage.
Publish Date	2015-08-08 13:26
Citation	Sobhonslidsuk A. Current position of vasoconstrictor and albumin infusion for type 1 hepatorenal syndrome. World J Gastrointest Phar­macol Ther 2015; 6(3): 28-31
URL	http://www.wjgnet.com/2150-5349/full/v6/i3/28.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v6.i3.28

Full Article (PDF)	WJGPT-6-28.pdf
Full Article (Word)	WJGPT-6-28.doc
Manuscript File	17942-Review.docx
Answering Reviewers	17942-Answering reviewers.pdf
Audio Core Tip	17942-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	17942-Conflict-of-interest statement.pdf
Copyright License Agreement	17942-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	17942-Language certificate.pdf
Peer-review Report	17942-Peer-review(s).pdf
Scientific Misconduct Check	17942-Scientific misconduct check.pdf
Scientific Editor Work List	17942-Scientific editor work list.pdf