Publication Name	World Journal of Gastroenterology
Manuscript ID	18092
Country	China

Received	2015-04-06 16:18
Peer-Review Started	2015-04-07 14:36
To Make the First Decision	2015-09-09 17:32
Return for Revision	2015-09-14 15:21
Revised	2015-09-28 10:16
Second Decision	2015-11-09 16:18
Accepted by Journal Editor-in-Chief	2015-11-11 16:46
Accepted by Executive Editor-in-Chief	2015-11-24 17:10
Articles in Press	2015-11-24 17:10
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-12-03 16:45
Typeset the Manuscript	2015-12-25 13:32
Publish the Manuscript Online	2016-01-15 14:54

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	New blood markers detection technology: A leap in the diagnosis of gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Maneesh K Beeharry, Wen-tao Liu, Min Yan and Zheng-gang Zhu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 30872477 National Natural Science Foundation of China 30901729
Corresponding Author	Wen-tao Liu, MD, PhD, Key Laboratory of Shanghai Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University, 197 Ruijin Road II, Shanghai 200025, China. wt_mygod@163.com
Key Words	Gastric cancer; Circulating tumor cells; Circulating tumor DNA; Proteomics; Biomarkers; Methylation
Core Tip	Gastric cancer (GC)’s poor prognosis has partly been a result of its late diagnosis due to its asymptomatic and nonspecific symptoms in its early stages. Tremendous advances in the OMICS technology have allowed the development of several methods helping to understand the mechanisms underlying gastric carcinogenesis, resulting in the identification of a large number of molecular targets such as circulating tumor cells, cell free DNA, cell tumor DNA and their sub-molecular components such as miRNA that show great promise as GC biomarkers. In this review, we are underlying the recent breakthroughs about new blood markers technology for GC while scrutinizing their potential clinical use in the pathogenesis, diagnosis and management of GC.
Publish Date	2016-01-15 14:54
Citation	Beeharry MK, Liu WT, Yan M, Zhu ZG. New blood markers detection technology: A leap in the diagnosis of gastric cancer. World J Gastroenterol 2016; 22(3): 1202-1212
URL	http://www.wjgnet.com/1007-9327/full/v22/i3/1202.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i3.1202

Full Article (PDF)	WJG-22-1202.pdf
Full Article (Word)	WJG-22-1202.doc
Manuscript File	18092-Review.docx
Answering Reviewers	18092-Answering reviewers.pdf
Audio Core Tip	18092-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18092-Conflict-of-interest statement.pdf
Copyright License Agreement	18092-Copyright assignment.pdf
Peer-review Report	18092-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18092-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18092-Scientific misconduct check.pdf
Scientific Editor Work List	18092-Scientific editor work list.pdf