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7/30/2015 11:19:00 AM | Browse: 1017 | Download: 2503
Publication Name World Journal of Gastroenterology
Manuscript ID 18117
Country China
Received
2015-04-07 17:29
Peer-Review Started
2015-04-08 08:29
To Make the First Decision
2015-05-18 13:08
Return for Revision
2015-05-20 17:34
Revised
2015-06-03 16:37
Second Decision
2015-07-02 21:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-07-03 17:03
Articles in Press
2015-07-03 17:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-07-14 14:36
Typeset the Manuscript
2015-07-21 17:04
Publish the Manuscript Online
2015-07-30 11:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Overexpression of chaperonin containing TCP1, subunit 3 predicts poor prognosis in hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Xiao Cui, Zhi-Ping Hu, Zhao Li, Peng-Ji Gao and Ji-Ye Zhu
Funding Agency and Grant Number
Funding Agency Grant Number
Beijing Key Laboratory Special Fund Z141107004414042.
Corresponding Author Ji-Ye Zhu, MM, Professor, Department of Hepatobiliary Surgery, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing 100044, China. gandanwk@vip.sina.com
Key Words Hepatocellular carcinoma; Subunit 3; Cell growth; Invasion; Prognosis
Core Tip Hepatocellular carcinoma (HCC) is a lethal disease and it is difficult to evaluate prognosis and manage the disease. This study showed that overexpression of chaperonin containing TCP1, subunit 3 (CCT3) in the nuclei of cancerous cells was an independent risk factor for the prognosis of HCC patients and was associated with tumor histological type and microvascular invasion. CCT3 affects activation of the interleukin-6/signal transducer and activator of transcription 3 signal pathway in vitro. CCT3 could play an essential role in the progression of HCC and might represent a prognostic biomarker in patients with HCC after hepatectomy.
Publish Date 2015-07-30 11:17
Citation Cui X, Hu ZP, Li Z, Gao PJ, Zhu JY. Overexpression of chaperonin containing TCP1, subunit 3 predicts poor prognosis in hepatocellular carcinoma. World J Gastroenterol 2015; 21(28): 8588-8604
URL http://www.wjgnet.com/1007-9327/full/v21/i28/8588.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i28.8588
Full Article (PDF) WJG-21-8588.pdf
Full Article (Word) WJG-21-8588.doc
Manuscript File 18117-Review.docx
Answering Reviewers 18117-Answering reviewers.pdf
Audio Core Tip 18117-Audio core tip.MP3
Biostatistics Review Certificate 18117-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 18117-Conflict-of-interest statement.pdf
Copyright License Agreement 18117-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 18117-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 18117-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 18117-Language certificate.PDF
Peer-review Report 18117-Peer-review(s).pdf
Scientific Misconduct Check 18117-Scientific misconduct check.pdf
Scientific Editor Work List 18117-Scientific editor work list.pdf