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Articles Published Processes
9/7/2015 4:31:00 PM | Browse: 1325 | Download: 2325
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Received |
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2015-04-09 16:52 |
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Peer-Review Started |
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2015-04-09 20:50 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2015-05-20 11:07 |
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Revised |
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2015-06-02 21:40 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2015-07-03 21:04 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2015-07-08 17:43 |
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Articles in Press |
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2015-07-08 17:43 |
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Edit the Manuscript by Language Editor |
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2015-07-27 08:18 |
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Typeset the Manuscript |
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2015-08-15 13:21 |
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Publish the Manuscript Online |
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2015-09-07 16:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Retrospective Study |
| Article Title |
Thyroid dysfunction in Chinese hepatitis C patients: Prevalence and correlation with TPOAb and CXCL10
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ren-Wen Zhang, Cui-Ping Shao, Na Huo, Min-Ran Li, Hong-Li Xi, Min Yu and Xiao-Yuan Xu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Major Project for Infectious Diseases Control |
2012ZX10002003-004-003 |
| National Natural Science Foundation of China |
8137305 |
| Doctoral Fund of Ministry of Education of China |
20090001110081 |
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| Corresponding Author |
Xiao-Yuan Xu, Professor, Department of Infectious Diseases, Peking University First Hospital, No. 8, Xishiku Street, Xicheng District, Beijing 100034, China. xiaoyuanxu6@163.com |
| Key Words |
Thyroid dysfunction; Thyroid peroxidase antibody; CXC chemokine ligand 10; Peginterferon alfa-2a/ribavirin; China |
| Core Tip |
We present novel data on the influence of peginterferon alfa-2a/ribavirin (PegIFNα-2a/RBV) on thyroid function in Chinese genotype 1 hepatitis C virus (HCV)-infected patients over a 48-wk treatment period. The results demonstrate that the prevalence of thyroid dysfunction (TD) was 18.0%. Lower pretreatment serum CXCL10 levels were associated with PegIFNα-2a/RBV induced TD in genotype 1 HCV-infected patients, and female patients exhibited an increased risk for developing TD compared with male patients. Baseline TPOAb positivity may also be a risk factor for TD development. However, most (84%) of the TD cases were reversible. To our knowledge, this is the first study to investigate the association of CXCL10 levels with PegIFNα-2a/RBV induced TD in genotype 1 HCV-infected patients in China. |
| Publish Date |
2015-09-07 16:31 |
| Citation |
Zhang RW, Shao CP, Huo N, Li MR, Xi HL, Yu M, Xu XY. Thyroid dysfunction in Chinese hepatitis C patients: Prevalence and correlation with TPOAb and CXCL10. World J Gastroenterol 2015; 21(33): 9765-9773 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i33/9765.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i33.9765 |
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