BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
12/17/2015 9:04:00 PM | Browse: 1108 | Download: 2440
 |
Received |
|
2015-04-10 08:24 |
|
Peer-Review Started |
|
2015-04-11 23:20 |
 |
First Decision by Editorial Office Director |
|
|
|
Return for Revision |
|
2015-06-24 14:25 |
|
Revised |
|
2015-07-09 11:36 |
|
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2015-09-14 10:17 |
|
Second Decision by Editor-in-Chief |
|
2015-09-17 20:17 |
|
Final Decision by Editorial Office Director |
|
2015-10-08 17:41 |
|
Articles in Press |
|
2015-10-08 17:41 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2015-11-27 19:49 |
|
Publish the Manuscript Online |
|
2015-12-17 21:04 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Allergy |
| Manuscript Type |
Basic Study |
| Article Title |
Platelet-rich plasma increases transforming growth factor-beta1 expression at graft-host interface following autologous osteochondral transplantation in a rabbit model
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lorraine A Boakye, Keir A Ross, John M Pinski, Niall A Smyth, Amgad M Haleem, Charles P Hannon, Lisa A Fortier and John G Kennedy |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Arteriocyte Inc. |
|
| Ohnell Family Foundation |
|
| Mr. and Mrs. Michael J Levitt |
|
|
| Corresponding Author |
John G Kennedy, MD, FRCS, Depart¬ment of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, United States. hannonc@hss.edu |
| Key Words |
Platelet rich plasma; Transforming growth factor-beta; Autologous osteochondral transplantation |
| Core Tip |
Despite the prevalence of platelet rich plasma (PRP) in both practice and literature, there is a dearth of data exploring the specific factors crucial to its role as an adjunct to cartilage repair surgeries. Our results suggest that the increased expression pattern of transforming growth factor-beta1 in PRP-treated rabbit femoral condyles, compared to saline treated controls, is associated with enhanced cartilage repair at the graft-host interface following autologous osteochondral transplantation. Our results serve as an initial step in building a body of evidence behind the specific growth factors crucial to cartilage repair and promise to help us understand how formulations of PRP are effective in musculoskeletal healing. |
| Publish Date |
2015-12-17 21:04 |
| Citation |
Boakye LA, Ross KA, Pinski JM, Smyth NA, Haleem AM, Hannon CP, Fortier LA, Kennedy JG. Platelet-rich plasma increases transforming growth factor-beta1 expression at graft-host interface following autologous osteochondral transplantation in a rabbit model. World J Orthop 2015; 6(11): 961-969
|
| URL |
http://www.wjgnet.com/2218-5836/full/v6/i11/961.htm |
| DOI |
http://dx.doi.org/10.5312/wjo.v6.i11.961 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
