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12/9/2015 6:37:00 PM | Browse: 559 | Download: 661
Publication Name World Journal of Clinical Oncology
Manuscript ID 18183
Country/Territory India
Received
2015-04-10 08:20
Peer-Review Started
2015-04-11 23:29
To Make the First Decision
2015-06-03 14:40
Return for Revision
2015-06-04 17:37
Revised
2015-08-04 15:01
Second Decision
2015-08-27 11:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-09-08 15:11
Articles in Press
2015-09-08 15:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-11-27 14:00
Publish the Manuscript Online
2015-12-09 18:37
ISSN 2218-4333 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Dentistry, Oral Surgery and Medicine
Manuscript Type Review
Article Title Dynamic role of myofibroblasts in oral lesions
Manuscript Source Unsolicited Manuscript
All Author List Neeta Bagul, Anjali Ganjre­, SN Goryawala, Rahul Kathariya and Shrikant Dusane
Funding Agency and Grant Number
Corresponding Author Dr. Rahul Kathariya, MDS, PhD, Department of Periodontology and Oral Implantology, Dr. D.Y Patil Dental College and Hospital, Dr. D. Y Patil Vidyapeeth, Sant Tukaram Nagar, Pimpri, Pune 411018, India. rkathariya@gmail.com
Key Words Myofibroblasts; Neoplasm; Fibroblasts; Precancerous lesions; Precancerous conditions; Carcinoma-associated fibroblasts
Core Tip Myofibroblast (MFs) are spindle-shaped cells consisting α-smooth muscle actin myofilament. They have a multicellular origin. MFs of the oral cavity have more contractile ability than dermal fibroblasts in physiologic wound healing. Recently, carcinoma-associated fibroblasts (CAFs) have received considerable attention because of their role in carcinogenesis. Mainly, transforming growth factor-β released from oral cancer cells is responsible for transforming fibroblasts into CAFs, which leads to tumour progression. However, the role of MFs in oral leukoplakia and oral submucous fibrosis is not completely understood. Understanding the implications of therapeutic approaches for the transdifferentiation of fibroblasts into MFs at different stages of carcinogenesis will facilitate in developing a treatment plan.
Publish Date 2015-12-09 18:37
Citation Bagul N, Ganjre A­, Goryawala SN, Kathariya R, Dusane S. Dynamic role of myofibroblasts in oral lesions. World J Clin Oncol 2015; 6(6): 264-271
URL http://www.wjgnet.com/2218-4333/full/v6/i6/264.htm
DOI http://dx.doi.org/10.5306/wjco.v6.i6.264
Full Article (PDF) WJCO-6-264.pdf
Full Article (Word) WJCO-6-264.doc
Manuscript File 18183-Review.docx
Answering Reviewers 18183-Answering reviewers.pdf
Audio Core Tip 18183-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 18183-Conflict-of-interest statement.pdf
Copyright License Agreement 18183-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 18183-Language certificate.pdf
Peer-review Report 18183-Peer-review(s).pdf
Scientific Misconduct Check 18183-Scientific misconduct check.pdf
Scientific Editor Work List 18183-Scientific editor work list.pdf