Publication Name	World Journal of Radiology
Manuscript ID	18185
Country	India

Received	2015-04-10 08:17
Peer-Review Started	2015-04-11 23:51
To Make the First Decision	2015-06-18 16:10
Return for Revision	2015-06-24 14:35
Revised	2015-08-17 22:12
Second Decision	2015-09-21 17:17
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-10-08 17:48
Articles in Press	2015-10-08 17:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-14 11:33
Publish the Manuscript Online	2015-10-26 10:35

ISSN	1949-8470 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Locoregional treatment for hepatocellular carcinoma: The best is yet to come
Manuscript Source	Invited Manuscript
All Author List	Naveen Kalra, Pankaj Gupta, Yogesh Chawla and Niranjan Khandelwal
Funding Agency and Grant Number
Corresponding Author	Naveen Kalra, MBBS, MD, Professor, Department of Radiodiagnosis and Imaging, PGIMER, Sector 12, Chandigarh 160012, India. navkal2004@yahoo.com
Key Words	Hepatocellular carcinoma; High intensity focussed ultrasound; Irreversible electroporation; Microwave ablation; Radiofrequency ablation
Core Tip	Treatment of hepatocellular carcinoma is dependent on the stage of disease. Early-stage disease is managed by resection. Radiofrequency ablation (RFA), is becoming an attractive alternative for very early-stage disease. Early-stage disease is treated with ablative therapies. RFA is the ablative therapy of choice. RFA, however, is not effective in all cases. Microwave ablation and irreversible electroporation are upcoming alternatives. Transarterial chemoembolization (TACE) is the modality of choice for intermediate-stage disease. TACE-based multimodal treatment is becoming acceptable. Advanced-stage disease is managed by sorafenib. However, TACE and radioembolization are other alternatives.
Publish Date	2015-10-26 10:35
Citation	Kalra N, Gupta P, Chawla Y, Khandelwal N. Locoregional treatment for hepatocellular carcinoma: The best is yet to come. World J Radiol 2015; 7(10): 306-318
URL	http://www.wjgnet.com/1949-8470/full/v7/i10/306.htm
DOI	http://dx.doi.org/10.4329/wjr.v7.i10.306

Full Article (PDF)	WJR-7-306.pdf
Full Article (Word)	WJR-7-306.doc
Manuscript File	18185-Review.doc
Answering Reviewers	18185-Answering reviewers.pdf
Audio Core Tip	18185-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	18185-Conflict-of-interest statement.pdf
Copyright License Agreement	18185-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18185-Language certificate.pdf
Peer-review Report	18185-Peer-review(s).pdf
Scientific Misconduct Check	18185-Scientific misconduct check.pdf
Scientific Editor Work List	18185-Scientific editor work list.pdf