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4/20/2016 11:11:00 PM | Browse: 988 | Download: 1856
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Received |
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2015-04-11 10:46 |
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Peer-Review Started |
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2015-04-11 11:31 |
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To Make the First Decision |
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2015-07-29 16:30 |
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Return for Revision |
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2015-08-01 19:08 |
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Revised |
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2015-09-09 00:00 |
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Second Decision |
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2015-11-27 15:53 |
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Accepted by Journal Editor-in-Chief |
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2015-11-27 22:56 |
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Accepted by Executive Editor-in-Chief |
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2016-01-22 15:46 |
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Articles in Press |
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2016-01-22 15:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-04-14 21:47 |
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Publish the Manuscript Online |
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2016-04-20 23:11 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Clinical utility of quantitative multi-antibody Polycheck immunoassays in the diagnosis of coeliac disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ewa Konopka, Maciej Grzywnowicz, Beata Oralewska, Joanna Cielecka-Kuszyk, Ilona Trojanowska and Bożena Cukrowska |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Children’s Memorial Health Institute |
S135/2013 |
| Children’s Memorial Health Institute |
229/14 |
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| Corresponding Author |
Bożena Cukrowska, Professor, Department of Pathology, the Children’s Memorial Health Institute, Aleja Dzieci Polskich 20, 04-730 Warsaw,
Poland. b.cukrowska@czd.pl
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| Key Words |
Coeliac disease; Tissue transglutaminase; Deamidated gliadin peptides; Multi-antibody tests; Polycheck celiac panels |
| Core Tip |
Detection of coeliac-specific antibodies has become a useful tool in the diagnostics of coeliac disease. Different serology test combinations have been found to improve diagnosis in comparison to a single antibody test. Recently, multi-antibody strategy has been implemented in immunoassays. In this study we have found that multi-parametric quantitative Polycheck immunoassay is reliable in reference to intestinal biopsy results and measurements of anti-tissue transglutaminase-IgA by a reference method. The best overall clinical performance was obtained by a combination of both IgA and IgG panels, with two and more positively detected antibodies, to determine the outcome.
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| Publish Date |
2016-04-20 23:11 |
| Citation |
Konopka E, Grzywnowicz M, Oralewska B, Cielecka-Kuszyk J, Trojanowska I, Cukrowska B. Clinical utility of quantitative multi-antibody Polycheck immunoassays in the diagnosis of coeliac disease. World J Gastrointest Pharmacol Ther 2016; 7(2): 254-260 |
| URL |
http://www.wjgnet.com/2150-5349/full/v7/i2/254.htm |
| DOI |
http://dx.doi.org/10.4292/wjgpt.v7.i2.254 |
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