Publication Name	World Journal of Hepatology
Manuscript ID	18262
Country	China

Received	2015-04-14 09:39
Peer-Review Started	2015-04-14 20:29
To Make the First Decision	2015-05-13 19:42
Return for Revision	2015-05-19 14:12
Revised	2015-05-26 14:23
Second Decision	2015-06-12 16:36
Accepted by Journal Editor-in-Chief	2015-06-12 17:04
Accepted by Company Editor-in-Chief	2015-06-19 18:07
Articles in Press	2015-06-19 18:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-24 10:33
Publish the Manuscript Online	2015-08-08 14:17

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Autophagy: A new therapeutic target for liver fibrosis
Manuscript Source	Invited Manuscript
All Author List	Yu-Qing Mao and Xiao-Ming Fan
Funding Agency and Grant Number	Funding Agency Grant Number Research grant from key clinical disciplines construction of Shanghai Municipality, China ZK2012B20
Corresponding Author	Xiao-Ming Fan, MD, PhD, Professor, Department of Gastroenterology, Jinshan Hospital of Fudan University, 1508 Longhang road, Shanghai 201508, China. xiaomingfan57@sina.com
Key Words	Autophagy; Liver fibrosis; Hepatic stellate cells; Antifibrotic target
Core Tip	Autophagy plays dual roles in hepatic fibrosis. On the one hand, it attenuates fibrosis by reducing hepatic injury via inhibiting inflammatory reaction and maintaining cellular homeostasis. On the other hand, it fuels activation of hepatic stellate cells (HSCs) by lipophagy and induces type?Ⅰ?collagen synthesis. More studies using Atg selective knockdown mice or primary HSCs derived from Atg-deleted mice are needed. Selective inhibition of autophagy in HSCs is an attractive antifibrotic strategy.
Publish Date	2015-08-08 14:17
Citation	Mao YQ, Fan XM. Autophagy: A new therapeutic target for liver fibrosis. World J Hepatol 2015; 7(16): 1982-1986
URL	http://www.wjgnet.com/1948-5182/full/v7/i16/1982.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i16.1982

Full Article (PDF)	WJH-7-1982.pdf
Full Article (Word)	WJH-7-1982.doc
Manuscript File	18262-Review.doc
Answering Reviewers	18262-Answering reviewers.pdf
Audio Core Tip	18262-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18262-Conflict-of-interest statement.pdf
Copyright License Agreement	18262-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18262-Language certificate.PDF
Peer-review Report	18262-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18262-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18262-Scientific misconduct check.pdf
Scientific Editor Work List	18262-Scientific editor work list.pdf