Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	18294
Country	Spain

Received	2015-04-15 08:27
Peer-Review Started	2015-04-17 09:02
To Make the First Decision	2015-06-25 17:55
Return for Revision	2015-07-01 10:02
Revised	2015-07-28 00:16
Second Decision	2015-09-14 10:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-09-28 17:42
Articles in Press	2015-09-28 17:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-03 19:43
Publish the Manuscript Online	2015-12-14 21:02

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Colorectal cancer diagnosis: Pitfalls and opportunities
Manuscript Source	Invited Manuscript
All Author List	Pablo Vega, Fátima Valentín and Joaquín Cubiella
Funding Agency and Grant Number	Funding Agency Grant Number Instituto de Salud Carlos III PI11/00094
Corresponding Author	Dr. Joaquín Cubiella, Department of Gastroenterology, Complexo Hospitalario Universitario de Ourense, Rua Ramón Puga 52-54, 32003 Ourense, Spain. joaquin.cubiella.fernandez@sergas.es
Key Words	Colorectal cancer; Colonoscopy; Primary health care; Faecal immunochemical test; Diagnostic yield; Diagnostic accuracy; Risk stratification; Open endoscopy unit; Practice guidelines; Health plan implementation
Core Tip	In this review, we summarize the pitfalls in the diagnostic procedure for colorectal cancer (CRC) in symptomatic patients. We collected the available information concerning the value of symptoms as predi-ctors of CRC and the factors involved in the delay of CRC diagnosis, including those related to the patient, to the physicians and to hospital delay. In this way, we review the currently available sets of appropriateness criteria for colonoscopy in symptomatic patients, the prioritization criteria and predictive models for CRC detection and, finally, the role of available biomarkers in the evaluation of symptomatic patients.
Publish Date	2015-12-14 21:02
Citation	Vega P, Valentín F, Cubiella J. Colorectal cancer diagnosis: Pitfalls and opportunities. World J Gastrointest Oncol 2015; 7(12): 422-433
URL	http://www.wjgnet.com/1948-5204/full/v7/i12/422.htm
DOI	http://dx.doi.org/10.4251/wjgo.v7.i12.422

Full Article (PDF)	WJGO-7-422.pdf
Full Article (Word)	WJGO-7-422.doc
Manuscript File	18294-Review.doc
Answering Reviewers	18294-Answering reviewers.pdf
Audio Core Tip	18294-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	18294-Conflict-of-interest statement.pdf
Copyright License Agreement	18294-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18294-Language certificate.pdf
Peer-review Report	18294-Peer-review(s).pdf
Scientific Misconduct Check	18294-Scientific misconduct check.pdf
Scientific Editor Work List	18294-Scientific editor work list.pdf