Publication Name	World Journal of Clinical Cases
Manuscript ID	18301
Country

Received	2015-04-15 11:01
Peer-Review Started	2015-04-18 18:29
To Make the First Decision	2015-05-13 19:40
Return for Revision	2015-05-19 15:06
Revised	2015-06-30 02:32
Second Decision	2015-07-29 16:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-08-07 16:25
Articles in Press	2015-08-07 16:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-26 16:01
Publish the Manuscript Online	2015-11-11 16:43

ISSN	2307-8960 (online)
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Category	Allergy
Manuscript Type	Case Report
Article Title	Differential diagnosis of a vanishing brain space occupying lesion in a child
Manuscript Source	Invited Manuscript
All Author List	Sherifa A Hamed, Mohamad A Mekkawy and Hosam Abozaid
Funding Agency and Grant Number
Corresponding Author	Dr. Sherifa A Hamed, MD, Consultant Neurologist, Professor, Department of Neurology and Psychiatry, Assiut University Hospital, Floor # 7, Room # 4, Assiut 71516, Egypt. hamed_sherifa@yahoo.com
Key Words	Vanishing brain mass; Gliosis; Unconfirmed diagnosis; Lymphoma; Granuloma
Core Tip	A vanishing brain space occupying lesion is defined as reduction or disappearance of a brain lesion spontaneously or after steroid treatment to ≤ 70% of its size before establishing its definitive diagnosis. A vanishing solitary neoplastic/non-neoplastic (pseudotumor) (e.g., infection/abscess, granuloma, radiation necrosis, multiple sclerosis) brain mass in a child poses a considerable diagnostic difficulty particularly deeply seated lesions in which tissue diagnosis is difficult to be done. In clinical practice, neuroimaging has to be done every 6-12 mo for at least 3-5 years to follow up after complete remission of the patient. Magnetic resonance spectroscopy (MRS) has been proved to be valuable for diagnostic differentiation between tumor and pseudotumor lesions. MRS provides information related to the metabolic activity in the culprit lesion (e.g., neoplastic processes, demyelination, cell necrosis or gliotic changes).
Publish Date	2015-11-11 16:43
Citation	Hamed SA, Mekkawy MA, Abozaid H. Differential diagnosis of a vanishing brain space occupying lesion in a child. World J Clin Cases 2015; 3(11): 956-964
URL	http://www.wjgnet.com/2307-8960/full/v3/i11/956.htm
DOI	http://dx.doi.org/10.12998/wjcc.v3.i11.956

Full Article (PDF)	WJCC-3-956.pdf
Full Article (Word)	WJCC-3-956.doc
Manuscript File	18301-Review.doc
Answering Reviewers	18301-Answering reviewers.pdf
Audio Core Tip	18301-Audio core tip.3ga
Conflict-of-Interest Disclosure Form	18301-Conflict-of-interest statement.pdf
Copyright License Agreement	18301-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	18301-Institutional review board statement.pdf
Peer-review Report	18301-Peer-review(s).pdf
Scientific Misconduct Check	18301-Scientific misconduct check.pdf
Scientific Editor Work List	18301-Scientific editor work list.pdf