Publication Name	World Journal of Gastroenterology
Manuscript ID	18352
Country	Italy

Received	2015-04-18 11:43
Peer-Review Started	2015-04-19 15:11
To Make the First Decision	2015-06-23 14:51
Return for Revision	2015-06-26 13:37
Revised	2015-07-07 22:13
Second Decision	2015-10-23 16:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-11-09 17:19
Articles in Press	2015-11-09 17:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-08 12:02
Publish the Manuscript Online	2016-01-15 14:54

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	How to predict clinical relapse in inflammatory bowel disease patients
Manuscript Source	Invited Manuscript
All Author List	Elisa Liverani, Eleonora Scaioli, Richard John Digby, Matteo Bellanova and Andrea Belluzzi
Funding Agency and Grant Number
Corresponding Author	Andrea Belluzzi, MD, Department of Medical and Surgical Sciences, University of Bologna, via Massarenti 9, 40138 Bologna, Italy. andrea.belluzzi@aosp.bo.it
Key Words	Crohn’s disease; Ulcerative colitis; Clinical relapse; Clinical predictors; Fecal calprotectin
Core Tip	Natural course of inflammatory bowel diseases (IBD) is mostly unpredictable so far. Predictors of benign or unfavourable clinical course are required to facilitate treatment strategies. Our aim is to review current evidence on the main clinical and biological markers to predict the aggressiveness of IBD and to discuss their prognostic role. No single marker is reliable as a flare predictor but a combination of clinical and biological indicators better serves our requirements; we propose an algorithm applicable in our daily practice, arising from a combination of clinical history and biological markers.
Publish Date	2016-01-15 14:54
Citation	Liverani E, Scaioli E, Digby RJ, Bellanova M, Belluzzi A. How to predict clinical relapse in inflammatory bowel disease patients. World J Gastroenterol 2016; 22(3): 1017-1033
URL	http://www.wjgnet.com/1007-9327/full/v22/i3/1017.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i3.1017

Full Article (PDF)	WJG-22-1017.pdf
Full Article (Word)	WJG-22-1017.doc
Manuscript File	18352-Review.docx
Answering Reviewers	18352-Answering reviewers.pdf
Audio Core Tip	18352-Audio core tip.mp3
Copyright License Agreement	18352-Copyright assignment.pdf
Peer-review Report	18352-Peer-review(s).pdf
Scientific Misconduct Check	18352-Scientific misconduct check.pdf
Scientific Editor Work List	18352-Scientific editor work list.pdf