Publication Name	World Journal of Diabetes
Manuscript ID	1837
Country	Canada

Received	2013-01-09 11:22
Peer-Review Started	2013-01-09 13:13
First Decision by Editorial Office Director
Return for Revision	2013-02-27 14:09
Revised	2013-03-07 00:10
Publication Fee Transferred
Second Decision by Editor	2013-06-19 12:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-06-19 23:36
Articles in Press
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-31 15:26
Publish the Manuscript Online	2013-08-15 11:51

ISSN	1948-9358 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Neurosciences
Manuscript Type	Autobiography
Article Title	Association of comorbidities with increasing severity of peripheral neuropathy in diabetes mellitus
Manuscript Source	Invited Manuscript
All Author List	Shafina Sachedina and Cory Toth
Funding Agency and Grant Number
Corresponding Author	Cory Toth, MD, Department of Clinical Neurosciences, the University of Calgary, HMRB 155, Foothills Hospital, 3330 Hospital Dr. NW, Calgary, Alberta T2N 2B1, Canada. cory.toth@albertahealthservices.ca
Key Words	Diabetic peripheral neuropathy; Comorbidities; Lipidemia; Cobalamin; Methylmalonic acid
Core Tip	The cause of diabetic peripheral neuropathy (DPN) has remained elusive. Comorbid conditions may contribute to the severity of DPN. We studied patients with type 1 or 2 diabetes and concurrent DPN in order to identify potential comorbid conditions associated with greater neuropathic deficit. Concurrent lipidemia was associated with worse DPN in either type 1 or 2 diabetes. A concurrent vitamin B12 deficiency increased severity of DPN in type 2 diabetes. Although our results were potentially confounded by higher HbA1C values in patients with comorbid conditions, vigilance should occur for other causes of PN when diabetes is present.
Publish Date	2013-08-15 11:51
Citation	Sachedina S, Toth C. Association of comorbidities with increasing severity of peripheral neuropathy in diabetes mellitus. World J Diabetes 2013; 4(4): 135-144
URL	http://www.wjgnet.com/1948-9358/full/v4/i4/135.htm
DOI	http://dx.doi.org/10.4239/wjd.v4.i4.135

Full Article (PDF)	WJD-4-135.pdf
Manuscript File	1837-Review.doc
Answering Reviewers	1837-Answering reviewers.pdf
Copyright License Agreement	1837-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics approval - interdisciplinary clinic for neuropathy and pain.jpg
Non-Native Speakers of English Editing Certificate	1837-Figures.ppt
Peer-review Report	1837-Peer review(s).pdf
Scientific Editor Work List	1837-Scientific editor work list.doc