Publication Name	World Journal of Gastroenterology
Manuscript ID	18428
Country	Japan

Received	2015-04-20 10:51
Peer-Review Started	2015-04-21 15:37
To Make the First Decision	2015-06-23 15:07
Return for Revision	2015-06-27 16:08
Revised	2015-07-23 10:13
Second Decision	2015-09-23 19:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-30 08:11
Articles in Press	2015-09-30 08:11
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-11-05 07:18
Typeset the Manuscript	2015-12-08 14:30
Publish the Manuscript Online	2016-01-15 14:54

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Antibody markers in the diagnosis of inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Keiichi Mitsuyama, Mikio Niwa, Hidetoshi Takedatsu, Hiroshi Yamasaki, Kotaro Kuwaki, Shinichiro Yoshioka, Ryosuke Yamauchi, Shuhei Fukunaga and Takuji Torimura
Funding Agency and Grant Number
Corresponding Author	Keiichi Mitsuyama, MD, PhD, Inflam­matory Bowel Disease Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan. ibd@med.kurume-u.ac.jp
Key Words	Biomarker; Crohn’s disease; Serological antibody; Ulcerative colitis
Core Tip	The diagnosis of inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is based on endoscopic, radiologic and histopathologic criteria. Recently, the search for a noninvasive marker that could augment or replace part of this diagnostic process has become a focus of IBD research. In this review, antibody markers, including microbial antibodies, autoantibodies and peptide antibodies, will be described, focusing on their common features. The discovery of novel IBD-specific and sensitive markers is anticipated. Such markers could minimize the use of endoscopic and radiologic examinations and could enable clinicians to implement individualized treatment plans designed to improve the long-term prognosis of patients with IBD.
Publish Date	2016-01-15 14:54
Citation	Mitsuyama K, Niwa M, Takedatsu H, Yamasaki H, Kuwaki K, Yoshioka S, Yamauchi R, Fukunaga S, Torimura T. Antibody markers in the diagnosis of inflammatory bowel disease. World J Gastroenterol 2016; 22(3): 1304-1310
URL	http://www.wjgnet.com/1007-9327/full/v22/i3/1304.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i3.1304

Full Article (PDF)	WJG-22-1304.pdf
Full Article (Word)	WJG-22-1304.doc
Manuscript File	18428-Review.doc
Answering Reviewers	18428-Answering reviewers.pdf
Audio Core Tip	18428-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	18428-Conflict-of-interest statement.pdf
Copyright License Agreement	18428-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18428-Language certificate.pdf
Peer-review Report	18428-Peer-review(s).pdf
Scientific Misconduct Check	18428-Scientific misconduct check.pdf
Scientific Editor Work List	18428-Scientific editor work list.pdf