Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	18448
Country	Türkiye

Received	2015-04-21 09:01
Peer-Review Started	2015-04-21 17:43
To Make the First Decision	2015-05-18 12:20
Return for Revision	2015-05-22 11:06
Revised	2015-07-07 18:10
Second Decision	2015-08-19 15:16
Accepted by Journal Editor-in-Chief	2015-08-19 16:50
Accepted by Executive Editor-in-Chief	2015-09-07 08:25
Articles in Press	2015-09-07 08:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-27 10:05
Publish the Manuscript Online	2015-11-17 12:17

ISSN	2150-5330 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Structural brain lesions in inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Can Dolapcioglu and Hatice Dolapcioglu
Funding Agency and Grant Number
Corresponding Author	Dr. Can Dolapcioglu, Department of Gastroenterology, Dr. Lutfi Kirdar Kartal Research and Training Hospital, Şemsi Denizer Cad. E-5 Karayolu Cevizli Mevkii Kartal, 34890 Istanbul, Turkey. candolapci@hotmail.com
Key Words	Inflammatory bowel disease; Ulcerative colitis; Crohn’s disease; Structural lesions; Magnetic resonance imaging; Brain lesions
Core Tip	Central nervous system complications or manifestations of inflammatory bowel disease deserve particular attention because symptomatic conditions can require early diagnosis and treatment, whereas unexplained manifestations might be linked to path-ogenic mechanisms. This review focuses on both symptomatic and asymptomatic brain lesions detectable on imaging studies, as well as their frequency and potential mechanisms. A direct causal relationship between inflammatory bowel disease and asymptomatic structural brain changes has not been demonstrated, but several possible explanations, including vasculitis, thromboembolism and malnutrition, have been proposed. Identification of the nature and potential mechanisms of brain lesions on imaging studies would improve patient care through early diagnosis and treatment.
Publish Date	2015-11-17 12:17
Citation	Dolapcioglu c, Dolapcioglu H. Structural brain lesions in inflammatory bowel disease. World J Gastrointest Pathophysiol 2015; 6(4): 124-130
URL	http://www.wjgnet.com/2150-5330/full/v6/i4/124.htm
DOI	http://dx.doi.org/10.4291/wjgp.v6.i4.124

Full Article (PDF)	WJGP-6-124.pdf
Full Article (Word)	WJGP-6-124.doc
Manuscript File	18448-Review.doc
Answering Reviewers	18448-Answering reviewers.pdf
Audio Core Tip	18448-Audio core tip.wma
Conflict-of-Interest Disclosure Form	18448-Conflict-of-interest statement.pdf
Copyright License Agreement	18448-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18448-Language certificate.pdf
Peer-review Report	18448-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18448-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18448-Scientific misconduct check.pdf
Scientific Editor Work List	18448-Scientific editor work list.pdf