Publication Name	World Journal of Gastroenterology
Manuscript ID	18522
Country	Türkiye

Received	2015-04-23 09:14
Peer-Review Started	2015-04-24 10:08
To Make the First Decision	2015-07-10 14:35
Return for Revision	2015-07-13 18:15
Revised	2015-07-23 18:52
Second Decision	2015-09-23 19:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-30 08:12
Articles in Press	2015-09-30 08:12
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-11-16 12:39
Typeset the Manuscript	2015-12-08 10:39
Publish the Manuscript Online	2015-12-24 11:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Endocrinology & Metabolism
Manuscript Type	Prospective Study
Article Title	Fatty liver disease: Disparate predictive ability for cardiometabolic risk and all-cause mortality
Manuscript Source	Unsolicited Manuscript
All Author List	Altan Onat, Günay Can, Ayşem Kaya, Tuğba Akbaş, Fatma Özpamuk-Karadeniz, Barış Şimşek, Hakan Çakır and Hüsniye Yüksel
Funding Agency and Grant Number	Funding Agency Grant Number Automotive company TOFAŞ, Istanbul, Turkey
Corresponding Author	Altan Onat, Professor, Department of Cardiology, Cerrahpaşa Medical Faculty, Istanbul University, Nisbetiye cad. 59/24, Etiler 34335, Istanbul, Turkey. alt_onat@yahoo.com.tr
Key Words	All-cause death; Coronary heart disease; Hepatic steatosis; Metabolic syndrome; Turkish adult risk factor study
Core Tip	We prospectively assessed in 1822 adults the association between a validated surrogate of fatty liver disease (FLD) and the incidence of type-2 diabetes, coronary heart disease (CHD), and all-cause mortality by stratifying to gender and using adjusted Cox regression models. At a mean 8 year follow-up, FLD was the major determinant of developing diabetes and was a significant predictor of CHD. Similarly-adjusted models for all-cause mortality did not confer risk, except for slightly in prediabetics and diabetic women. Involvement of circulating lipoprotein(a) in autoimmune activation may be an underlying mechanism. Such a FLD surrogate may be used in epidemiologic studies.
Publish Date	2015-12-24 11:11
Citation	Onat A, Can G, Kaya A, Akbaş T, Özpamuk-Karadeniz F, Şimşek B, Çakır H, Yüksel H. Fatty liver disease: Disparate predictive ability for cardiometabolic risk and all-cause mortality. World J Gastroenterol 2015; 21(48): 13555-13565
URL	http://www.wjgnet.com/1007-9327/full/v21/i48/13555.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i48.13555

Full Article (PDF)	WJG-21-13555.pdf
Full Article (Word)	WJG-21-13555.doc
Manuscript File	18522-Review.doc
Answering Reviewers	18522-Answering reviewers.pdf
Audio Core Tip	18522-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	18522-Conflict-of-interest statement.pdf
Copyright License Agreement	18522-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	18522-Institutional review board statement.pdf
Peer-review Report	18522-Peer-review(s).pdf
Scientific Misconduct Check	18522-Scientific misconduct check.pdf
Scientific Editor Work List	18522-Scientific editor work list.pdf