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Articles Published Processes
1/31/2016 7:20:00 PM | Browse: 923 | Download: 1476
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Received |
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2015-04-24 16:43 |
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Peer-Review Started |
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2015-04-29 12:15 |
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To Make the First Decision |
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2015-06-03 14:20 |
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Return for Revision |
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2015-06-09 11:10 |
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Revised |
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2015-08-27 01:01 |
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Second Decision |
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2015-11-02 14:11 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2015-11-11 17:47 |
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Articles in Press |
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2015-11-11 17:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-01-23 20:13 |
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Publish the Manuscript Online |
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2016-01-31 19:20 |
| ISSN |
2218-6220 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Obstetrics & Gynecology |
| Manuscript Type |
Basic Study |
| Article Title |
Alpha1B adrenoceptor expression is a marker of reduced survival and increased tumor recurrence in patients with endometrioid ovarian cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Dascha Deutsch, Suha Deen, Frank Entschladen, Clare Coveney, Robert Rees, Kurt S Zänker and Desmond George Powe |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fritz Bender Foundation (Munich; to Dascha Deutsch, Frank Entschladen and Kurt S Zänker) |
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| Nottingham University Hospital Trustees |
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| Corresponding Author |
Desmond George Powe, PhD, Principal Healthcare Research Scientist, Department of Cellular Pathology, Queens Medical Centre, Nottingham University Hospitals Trust, Derby Road, Nottingham NG7 2UH,
United Kingdom. des.powe@nottingham.ac.uk
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| Key Words |
Alpha adrenoceptor; Beta adrenoceptor; b-blockers; a-blockers; Ovarian cancer; Prognosis; Cancer therapy |
| Core Tip |
Epidemiological studies suggest that b-blockers might have a role in reducing metastatic spread and tumor recurrence and thereby prolong patient survival in some cancer types. In this novel study we found a1B adrenoceptor is a biomarker of tumor recurrence in endometrioid ovarian cancer. Further studies are needed to test if selective a1 adrenergic receptor antagonists inhibit tumor recurrence and prolong survival in patients with this type of cancer.
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| Publish Date |
2016-01-31 19:20 |
| Citation |
Deutsch D, Deen S, Entschladen F, Coveney C, Rees R, Zänker KS, Powe DG. Alpha1B adrenoceptor expression is a marker of reduced survival and increased tumor recurrence in patients with endometrioid ovarian cancer. World J Obstet Gynecol 2016; 5(1): 118-126 |
| URL |
http://www.wjgnet.com/2218-6220/full/v5/i1/118.htm |
| DOI |
http://dx.doi.org/10.5317/wjog.v5.i1.118 |
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