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Articles Published Processes
9/12/2014 8:41:00 PM | Browse: 1276 | Download: 1564
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Received |
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2013-01-10 13:39 |
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Peer-Review Started |
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2013-01-11 11:31 |
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To Make the First Decision |
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2013-03-04 11:51 |
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Return for Revision |
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2013-03-08 11:30 |
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Revised |
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2013-04-11 10:58 |
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Second Decision |
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2013-06-06 09:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-06-06 12:32 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-09-07 14:16 |
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Publish the Manuscript Online |
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2013-09-21 09:08 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Autobiography |
Article Title |
Modulation of individual components of gastric motor response to duodenal glucose
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Manuscript Source |
Invited Manuscript |
All Author List |
Adam M Deane, Laura K Besanko, Carly M Burgstad, Marianne J Chapman, Michael Horowitz and Robert JL Fraser |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
A project grant from the Royal Adelaide Hospital |
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Corresponding Author |
Dr. Adam M Deane, Intensive Care Unit, Level 4, Emergency Services Building, Royal Adelaide Hospital, North Terrace, Adelaide 5000, South Australia, Australia. adam.deane@adelaide.edu.au |
Key Words |
Glucose; Gastrointestinal motility; Pyloric; Antral; Duodenum; Manometry; Motor activity; Blood glucose |
Core Tip |
Antro-pyloro-duodenal manometry was performed in 15 healthy subjects. Subjects were randomly given 20 min intraduodenal infusions of glucose at 0, 0.5, 1.0 and 1.5 kcal/min. Intraduodenal glucose infusion acutely increased isolated pyloric pressure wave frequency and pyloric tone and decreased antral wave frequency in a dose-dependent fashion. A threshold for stimulation was observed at 1.0 kcal/min for pyloric phasic pressure waves and 1.5 kcal/min for pyloric tone and antral contractility. These data suggest that there is hierarchy for the activation of gastrointestinal motor responses to small intestinal glucose stimulation. |
Publish Date |
2013-09-21 09:08 |
Citation |
Deane AM, Besanko LK, Burgstad CM, Chapman MJ, Horowitz M, Fraser RJL. Modulation of individual components of gastric motor response to duodenal glucose. World J Gastroenterol 2013; 19(35): 5863-5869 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i35/5863.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i35.5863 |
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