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8/26/2015 8:56:00 PM | Browse: 648 | Download: 999
Publication Name World Journal of Diabetes
Manuscript ID 18617
Country/Territory United States
2015-04-25 10:45
Peer-Review Started
2015-04-28 16:43
To Make the First Decision
2015-06-03 14:21
Return for Revision
2015-06-09 11:25
2015-06-15 23:41
Second Decision
2015-08-12 18:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-08-17 12:01
Articles in Press
2015-08-17 12:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-08-22 19:46
Publish the Manuscript Online
2015-08-26 20:56
ISSN 1948-9358 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac and Cardiovascular Systems
Manuscript Type Basic Study
Article Title Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats
Manuscript Source Invited Manuscript
All Author List María J Crespo and José Quidgley
Funding Agency and Grant Number
Funding Agency Grant Number
MBRS-RISE R25-GM061838
RCMI G12-RR03051
Corresponding author Dr. María J Crespo, Departments of Physiology and Anesthesiology, University of Puerto Rico School of Medicine, GPO Box 365067, San Juan, PR 00936 5067, United States. maria.crespo3@upr.edu
Keywords Statins; Diabetes; Oxidative stress; Cardiac function; Perivascular fibrosis
Core Tip Despite evidence that statins are useful therapeutic tools in treating diabetes, questions remain as to whether their effects are drug-specific or class-dependent, what mechanisms underlie these effects, and which statin is the most appropriate. We found that atorvastatin, simvastatin, and pravastatin are equally effective in improving cardiovascular performance in Type 1 diabetic rats, and that the observed benefits are likely to be secondary to the reduction of oxidative stress by these drugs.
Publish Date 2015-08-26 20:56
Citation Crespo MJ, Quidgley J. Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats. World J Diabetes 2015; 6(10): 1168-1178
Url http://www.wjgnet.com/1948-9358/full/v6/i10/1168.htm
DOI http://dx.doi.org/10.4239/wjd.v6.i10.1168
Full Article (PDF) WJD-6-1168.pdf
Full Article (Word) WJD-6-1168.doc
Manuscript File 18617-Review.docx
Answering Reviewers 18617-Answering reviewers.pdf
Audio Core Tip 18617-Audio core tip.wav
Biostatistics Review Certificate 18617-Biostatistics statement.PDF
Conflict-of-Interest Disclosure Form 18617-Conflict-of-interest statement.PDF
Copyright License Agreement 18617-Copyright assignment.pdf
Data Sharing Statement 18617-Data sharing statement.PDF
Institutional Animal Care and Use Committee Approval Form or Document 18617-Institutional animal care and use committee statement.PDF
Institutional Review Board Approval Form or Document 18617-Institutional review board statement.pdf
Peer-review Report 18617-Peer-review(s).pdf
Scientific Misconduct Check 18617-Scientific misconduct check.pdf
Scientific Editor Work List 18617-Scientific editor work list.pdf