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Articles Published Processes
8/26/2015 8:56:00 PM | Browse: 1534 | Download: 2830
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Received |
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2015-04-25 10:45 |
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Peer-Review Started |
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2015-04-28 16:43 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2015-06-09 11:25 |
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Revised |
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2015-06-15 23:41 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2015-08-12 18:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2015-08-17 12:01 |
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Articles in Press |
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2015-08-17 12:02 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-08-22 19:46 |
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Publish the Manuscript Online |
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2015-08-26 20:56 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Basic Study |
| Article Title |
Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats
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| Manuscript Source |
Invited Manuscript |
| All Author List |
María J Crespo and José Quidgley |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| MBRS-RISE |
R25-GM061838 |
| RCMI |
G12-RR03051 |
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| Corresponding Author |
Dr. María J Crespo, Departments of Physiology and Anesthesiology, University of Puerto Rico School of Medicine, GPO Box 365067, San Juan, PR 00936 5067, United States. maria.crespo3@upr.edu |
| Key Words |
Statins; Diabetes; Oxidative stress; Cardiac function; Perivascular fibrosis |
| Core Tip |
Despite evidence that statins are useful therapeutic tools in treating diabetes, questions remain as to whether their effects are drug-specific or class-dependent, what mechanisms underlie these effects, and which statin is the most appropriate. We found that atorvastatin, simvastatin, and pravastatin are equally effective in improving cardiovascular performance in Type 1 diabetic rats, and that the observed benefits are likely to be secondary to the reduction of oxidative stress by these drugs. |
| Publish Date |
2015-08-26 20:56 |
| Citation |
Crespo MJ, Quidgley J. Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats. World J Diabetes 2015; 6(10): 1168-1178 |
| URL |
http://www.wjgnet.com/1948-9358/full/v6/i10/1168.htm |
| DOI |
http://dx.doi.org/10.4239/wjd.v6.i10.1168 |
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