Publication Name	World Journal of Diabetes
Manuscript ID	18617
Country	United States

Received	2015-04-25 10:45
Peer-Review Started	2015-04-28 16:43
To Make the First Decision	2015-06-03 14:21
Return for Revision	2015-06-09 11:25
Revised	2015-06-15 23:41
Second Decision	2015-08-12 18:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-08-17 12:01
Articles in Press	2015-08-17 12:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-22 19:46
Publish the Manuscript Online	2015-08-26 20:56

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Basic Study
Article Title	Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats
Manuscript Source	Invited Manuscript
All Author List	María J Crespo and José Quidgley
Funding Agency and Grant Number	Funding Agency Grant Number MBRS-RISE R25-GM061838 RCMI G12-RR03051
Corresponding Author	Dr. María J Crespo, Departments of Physiology and Anesthesiology, University of Puerto Rico School of Medicine, GPO Box 365067, San Juan, PR 00936 5067, United States. maria.crespo3@upr.edu
Key Words	Statins; Diabetes; Oxidative stress; Cardiac function; Perivascular fibrosis
Core Tip	Despite evidence that statins are useful therapeutic tools in treating diabetes, questions remain as to whether their effects are drug-specific or class-dependent, what mechanisms underlie these effects, and which statin is the most appropriate. We found that atorvastatin, simvastatin, and pravastatin are equally effective in improving cardiovascular performance in Type 1 diabetic rats, and that the observed benefits are likely to be secondary to the reduction of oxidative stress by these drugs.
Publish Date	2015-08-26 20:56
Citation	Crespo MJ, Quidgley J. Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats. World J Diabetes 2015; 6(10): 1168-1178
URL	http://www.wjgnet.com/1948-9358/full/v6/i10/1168.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i10.1168

Full Article (PDF)	WJD-6-1168.pdf
Full Article (Word)	WJD-6-1168.doc
Manuscript File	18617-Review.docx
Answering Reviewers	18617-Answering reviewers.pdf
Audio Core Tip	18617-Audio core tip.wav
Biostatistics Review Certificate	18617-Biostatistics statement.PDF
Conflict-of-Interest Disclosure Form	18617-Conflict-of-interest statement.PDF
Copyright License Agreement	18617-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	18617-Institutional animal care and use committee statement.PDF
Institutional Review Board Approval Form or Document	18617-Institutional review board statement.pdf
Peer-review Report	18617-Peer-review(s).pdf
Scientific Misconduct Check	18617-Scientific misconduct check.pdf
Scientific Editor Work List	18617-Scientific editor work list.pdf