Publication Name	World Journal of Clinical Oncology
Manuscript ID	18735
Country	United Kingdom

Received	2015-04-27 08:24
Peer-Review Started	2015-04-27 08:40
To Make the First Decision	2015-06-18 15:30
Return for Revision	2015-06-24 18:01
Revised	2015-08-01 17:21
Second Decision	2015-08-27 11:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-08 15:15
Articles in Press	2015-09-08 15:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-28 15:26
Publish the Manuscript Online	2015-12-09 18:37

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Adjuvant chemotherapy for rectal cancer: Is it needed?
Manuscript Source	Invited Manuscript
All Author List	Kristijonas Milinis, Michael Thornton, Amir Montazeri and Paul S Rooney
Funding Agency and Grant Number
Corresponding Author	Paul S Rooney, MBChB, FRCS, DM, Department of Colorectal Surgery, the Royal Liverpool Univer­sity Hospital, Prescot Street, Merseyside, Liverpool L7 8XP, United Kingdom. paul.rooney@rlbuht.nhs.uk
Key Words	Rectal cancer; Adjuvant chemotherapy
Core Tip	Adjuvant chemotherapy for rectal cancer is a contentious issue despite its widespread use. Recent randomised controlled trials have shown no benefit in survival of adjuvant chemotherapy in patients treated with preoperative chemoradiotherapy. It is becoming evident that not all patients benefit from adjuvant chemotherapy and identification of these patients should be the focus of future studies. The present review discusses the current evidence-base for adjuvant chemotherapy in rectal cancer and provides directions for future research.
Publish Date	2015-12-09 18:37
Citation	Milinis K, Thornton M, Montazeri A, Rooney PS. Adjuvant chemotherapy for rectal cancer: Is it needed? World J Clin Oncol 2015; 6(6): 225-236
URL	http://www.wjgnet.com/2218-4333/full/v6/i6/225.htm
DOI	http://dx.doi.org/10.5306/wjco.v6.i6.225

Full Article (PDF)	WJCO-6-225.pdf
Full Article (Word)	WJCO-6-225.doc
Manuscript File	18735-Review.docx
Answering Reviewers	18735-Answering reviewers.pdf
Audio Core Tip	18735-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18735-Conflict-of-interest statement.pdf
Copyright License Agreement	18735-Copyright assignment.pdf
Peer-review Report	18735-Peer-review(s).pdf
Scientific Misconduct Check	18735-Scientific misconduct check.pdf
Scientific Editor Work List	18735-Scientific editor work list.pdf