Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	18744
Country	Taiwan

Received	2015-04-27 10:54
Peer-Review Started	2015-05-01 13:59
To Make the First Decision	2015-05-18 13:06
Return for Revision	2015-05-20 16:51
Revised	2015-06-10 14:07
Second Decision	2015-09-13 22:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-15 16:50
Articles in Press	2015-09-15 16:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-20 15:47
Publish the Manuscript Online	2015-11-12 18:51

ISSN	2150-5349 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Helicobacter pylori: Effect of coexisting diseases and update on treatment regimens
Manuscript Source	Invited Manuscript
All Author List	Shen-Shong Chang and Hsiao-Yun Hu
Funding Agency and Grant Number
Corresponding Author	Hsiao-Yun Hu, PhD, Department of Education and Research, Taipei City Hospital, No. 145 Zhengzhou Rd., Taipei 103, Taiwan. hyhu@ym.edu.tw
Key Words	Concomitant diseases; Helicobacter pylori; Culture susceptibility; Concomitant therapy; Hybrid therapy
Core Tip	The authors outline that patients contracting concomitant diseases have an increased risk of developing ulcer disease through pathogenic mechanisms distinct from those of Helicobacter pylori (H. pylori) infections. Early H. pylori eradication is associated with a reduced risk of recurrent complicated peptic ulcers in patients with end stage renal disease and liver cirrhosis. Two novel eradication regimens, namely concomitant and hybrid therapy, have proven more effective in patients with dual resistant H. pylori strains. High-dose amoxicillin therapy is promising and superior to standard regimens. Finally, culture and susceptibility testing should be performed before third-line treatment.
Publish Date	2015-11-12 18:51
Citation	Chang SS, Hu HY. Helicobacter pylori: Effect of coexisting diseases and update on treatment regimens. World J Gastrointest Pharmacol Ther 2015; 6(4): 127-136
URL	http://www.wjgnet.com/2150-5349/full/v6/i4/127.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v6.i4.127

Full Article (PDF)	WJGPT-6-127.pdf
Full Article (Word)	WJGPT-6-127.doc
Manuscript File	18744-Review.docx
Answering Reviewers	18744-Answering reviewers.pdf
Audio Core Tip	18744-Audio core tip.MP3
Conflict-of-Interest Disclosure Form	18744-Conflict-of-interest statement.pdf
Copyright License Agreement	18744-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20150427100430.pdf
Peer-review Report	18744-Peer-review(s).pdf
Scientific Misconduct Check	18744-Scientific misconduct check.pdf
Scientific Editor Work List	18744-Scientific editor work list.pdf